The gynecologic oncology team at Froedtert & the Medical College of Wisconsin is involved with nationwide groups such as NRG and the GOG Foundation. These groups consist of Gynecologic Oncologists, Medical Oncologists, Pathologists, Radiation Oncologists, and many scientific researchers from around the US and the world.
Open to Enrollment
| Type of Research | Protocol ID & Study Title |
|---|---|
| Observational | Slow Heart Registry PI: Erika Peterson, MD A prospective observational cohort study of fetal immune-mediated high-degree heart block. Keywords: Pregnancy, Heart Block |
| Interventional, Registry | Fetal Atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial PI: Erika Peterson, MD This multicenter randomized clinical trial aims to evaluate which standard medication (or combination of medications) for treatment of fetal supraventricular tachyarrhythmias is safest and most effective. Women who are not eligible for the randomized trial or who do not wish to participate may still be eligible to enroll in the observational registry. Keywords: Pregnancy, Arrhythmia |
| Registry | NAFTNet 01-13: Complicated Monochorionic Twin Pregnancy Registry PI: Erika Peterson, MD Keywords: Pregnancy, Monochorionic Twins, Registry |
| Interventional | Gestational Diabetes and Pharmacotherapy (GAP)- A Randomized Controlled Trial Investigating Timing of Pharmacotherapy Initiation for Patients with Gestational Diabetes PI: Anna Palatnik, MD The goal of this study is to compare two different thresholds for initiation of medical treatment for gestational diabetes mellitus (GDM). Pregnant women diagnosed with GDM will be randomized to either start pharmacotherapy when they have reached at least 20% or at least 40% of capillary blood glucose (CBG) values above the target goal. The investigators hypothesize that a lower threshold of 20% elevated CBG levels, compared to 40%, will lead to lower rates of obstetric and medical complications. Keywords: pregnancy, gestational diabetes, standardization of care |
| Interventional | A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix (PROSPECT) PI: Anna Palatnik, MD A Randomized Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation with a Short Cervix (PROSPECT) Keywords: Pregnancy, Twins, Short Cervix, Progesterone, Pessary |
| Interventional | Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia (REPAIR) PI: Anna Palatnik, MD A multicenter randomized controlled trial of postpartum patients with hypertensive disorders of pregnancy randomized to intensive blood pressure control versus usual care during the first 6 weeks postpartum. The study will take place at two clinical sites: Medical College of Wisconsin (MCW) and Northwestern University (NU). All participants will undergo BP monitoring, cardiovascular function assessment, and collection of cardiovascular biomarkers at baseline, 6 weeks, and 12 months postpartum. The primary outcome is a new diagnosis of stage I hypertension at one year postpartum. Keywords: Pregnancy, Preeclampsia, Cardiovascular Health |
| Observational | Preconception To Toddler Study (PTTS) PI: Jennifer McIntosh, DO, MS Tracks health outcomes from the pre-pregnancy period through gestation and up to two years post-delivery, supporting women and children’s health research. Keywords: Pregnancy, Preconception, Post-delivery |
| Registry | Novel Role for Placental Endothelial Mitochondrial Dysfunction in Preeclampsia PI: Jennifer McIntosh, DO, MS This study uses placental, plasma, and cord blood samples to study changes in placental blood vessels and evaluate potential treatments for preeclampsia. Keywords: Placental, Preeclampsia |
| Observational | Impact of Non-Nutritive Sweeteners on placental drug transporters. PI: Stephanie Olivier-Van Stichelen, PhD This study assess the consumption of non-nutritive sweeteners (Sucralose, Acesulfame-K , Sacharin…) during pregnancy and their impact on the expression of placental transporters for drugs and fetal waste. Keywords: Placental, Pregnancy, Preconception, Post-delivery |
| Observational | Placental Protein glycosylation in gestational diabetes. PI: Stephanie Olivier-Van Stichelen, PhD We are studying the relationship between the O-GlcNAcylation of protein and the production of placental hormones to understand better what triggers gestational diabetes and other gestational complications. Keywords: Placental, Pregnancy, Placental, Gestational Diabetes |