Keguo Li, PhD
Dr. Li joined the Department of Obstetrics and Gynecology as an instructor in April, 2015. Before that, he was a research scientist in Dr. Ramchandran’s lab at the Medical College of Wisconsin (MCW). He received his postdoctoral training in developmental biology at Sun Yat-sen University, China and in cardiovascular biology at MCW. He completed his PhD in cell biology at the Institute of Zoology, Chinese Academy of Sciences.
Dr. Li’s research focuses on disabling blood vessels surrounding gynecologic cancers. The blood vessels nourish and transport cancer cells. By targeting the integrity of vascular wall, his research aims to make newly formed blood vessels nonfunctional. This way, nutrient and oxygen cannot be transported to cancer area, nor can cancer cells move away. One of such targets is DLL4. Dr. Li identified a regulatory RNA molecule at DLL4 locus. He is trying to translate the RNA molecule into an anti-cancer agent.
The Medical College of Wisconsin (MCW) has received a four-year, $1.8 million dollar grant from the National Institutes of Health’s National Heart, Lung and Blood… Read More ›