Huang, Yi-Wen, PhD

Yi-Wen Huang, PhD

Assistant Professor

(414) 955-2945

Introduction

Yi-Wen Huang, PhDDr. Huang is an Assistant Professor at the Department of Obstetrics and Gynecology, Medical College of Wisconsin in July, 2012. He received his Ph.D. in the Veterinary Biosciences, College of Veterinary Medicine at Ohio State University in June, 2006. After that, he joined Dr. Tim Huang’s laboratory as a post-doctoral researcher to study on epigenetics, specifically on DNA methylation at Ohio State University.

Dr. Huang’s research interests are investigating the roles of epigenetics in cancer development. He has extensive experience in using methylation microarray technology to identify candidate epigenetic biomarkers for disease detection and recurrence in ovarian and endometrial cancers. He also has experience in studying DNA methylation changes using next-generation sequencing. Applying this technique, Dr. Huang generated more than half billions of sequencing bases from more than 200 primary endometrial and breast specimens, and elucidated specific DNA methylator phenotypes.

His laboratory focuses on identifying epigenetic changes involved in the endometrial tumorigenesis. Currently, a mouse model was applied to understand how obesity might contribute to endometrial cancer development and how chemopreventive agents such as berries might suppress this disease.

Dr. Huang has 35 peer reviewed publications and 2 book chapters.

Publications

Research

Principal InvestigatorTitle of Research Study
Awards / Publications / Presentations
Huang, Yi-Wen, PhDMicroRNA and Gynecologic Cancers
Huang, Yi-Wen, PhDChemoprevention of high-fat diet induced endometrial cancer by berries
Huang, Yi-Wen, PhDIn utero exposure of high fat diets and endometrial tumorigenesis
Huang, Yi-Wen, PhDTargeting miR-137-KDM1A in endometrial cancer

In the News

Yi-Wen Huang, PhD, Receives Athena’s Run Endometrial Cancer Research Grant

Yi-Wen Huang, PhD, Receives Athena’s Run Endometrial Cancer Research Grant

01/30/2015  |  Department News

The Foundation for Women’s Cancer Research Grants & Awards Committee has selected Dr. Huang’s research application entitled “Targeting the miR-137-KDM1 axis as a therapeutic strategy… Read More ›

Lab

Huang Lab

Huang Lab

Endometrial cancer is the most common gynecological cancer among women in the United States. Large-scale epidemiological studies have demonstrated that obesity increases the risk of… Read More ›