Clinical Trials and Research for General OBGYN

Open to Enrollment
Closed to Enrollment

Open to Enrollment

Type of Research	Protocol ID & Study Title
Interventional, Registry	Fetal Atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial PI: Erika Peterson, MD This multicenter randomized clinical trial aims to evaluate which standard medication (or combination of medications) for treatment of fetal supraventricular tachyarrhythmias is safest and most effective. Women who are not eligible for the randomized trial or who do not wish to participate may still be eligible to enroll in the observational registry. Keywords: Pregnancy, Arrhythmia
Registry	NAFTNet 01-13: Complicated Monochorionic Twin Pregnancy Registry PI: Erika Peterson, MD Keywords: Pregnancy, Monochorionic Twins, Registry
Interventional	Chronic Hypertension and Pregnancy (CHAP) PI: Anna Palatnik, MD This multicenter randomized clinical trial aims to evaluate whether a blood pressure treatment strategy during pregnancy to achieve targets that are recommended for non-pregnant reproductive-age adults (<140/90 mmHg) is effective and safe when compared to the ACOG- recommended standard during pregnancy (no treatment unless BP is severe). Keywords: Pregnancy, Chronic hypertension
Interventional	TOPS PI: Anna Palatnik, MD A randomized Trial of Pessary in Singleton Pregnancies with a Short Cervix. This multicenter, randomized clinical trial aims to determine whether using a pessary in singleton pregnancies that are complicated by a short cervix (less than or equal to 20mm) reduces the risk of premature birth. Keywords: Pregnancy, Pre-eclampsia
Interventional	A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix (PROSPECT) PI: Anna Palatnik, MD A Randomized Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation with a Short Cervix (PROSPECT) Keywords: Pregnancy, Twins, Short Cervix, Progesterone, Pessary
Observational	Activity in Women At Risk for Early delivery (AWARE) PI: Anna Palatnik, MD Keywords: Pregnancy, Short Cervix, Activity Level
Registry	Maternal Morbidity and Mortality during the COVID-19 Pandemic (MFMU COVID) PI: Anna Palatnik, MD Keywords: Pregnancy, COVID-19
Interventional	Preeclamptic Postpartum Antihypertensive Treatment (P-PAT) A Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women with Preeclampsia PI: Anna Palatnik, MD Keywords: Pregnancy, Pre-Eclampsia, Gestational Hypertension
Observational	Effects of Preeclampsia and Preterm Birth on Maternal Endothelial Function (PREEMA) A Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women with Preeclampsia PI: Jennifer McIntosh, MD Keywords: Pregnancy, Pre-Eclampsia, Pre-Term Birth

Closed to Enrollment

Type of Trial	Protocol ID & Study Title
Uterine Fibroids	Uterine Fibroids Title: A Phase 2b Study to Evaluate the Safety and Efficacy of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids Keywords: Uterine Fibroids, Heavy Bleeding, Elagolix
Interventional	Progenity PRO-104-Preeclampsia PI: Anna Palatnik, MD This sample collection study obtains blood and urine samples from pregnant women who present with clinical suspicion of preeclampsia. Samples will be used to evaluate and validate the performance of an assay intended to aid in assessing the risk of preeclampsia. Keywords: Pregnancy, Pre-eclampsia, Hypertension
Interventional	AMAG-423-201 PI: Anna Palatnik, MD A Phase 2b/3a, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Efficacy and Safety of AMAG-423, a Digoxin Immune Fab, in Antepartum Subjects With Severe Preeclampsia Keywords: Pregnancy, Pre-eclampsia

To obtain information regarding any gynecologic clinical trials that our department has open, please contact our research team at 1-855-771-9477 or Email Us.