13 Sep Role of Vascular Smooth Muscle RhoBTB1/Cullin-3 in Hy-pertension: A Role in Preeclampsia? – Curt Sigmund, PhD
Curt D. Sigmund, PhD
James J. Smith & Catherine Welsch Smith Professor and Chair, Department of Physiology
Associate Director, Cardiovascular Center
Medical College of Wisconsin
Dr. Sigmund’s Research
Dr. Sigmund’s major areas of research focus on central nervous system and vascular mechanisms of blood pressure regulation by the renin-angiotensin system, the transcription factor PPAR-gamma, and its downstream effectors Cullin-3/RhoBTB1, investigating these using a combination of molecular biological, genetic and physiological approaches including the generation of unique transgenic and knockout models. Dr. Sigmund’s laboratory is located within the Cardiovascular Center in the Health Research Center and Medical Education buildings.