Calendar of Events
Featured Speaker: AnnaMarie Connolly, MD, FACOG – “We Can All Agree: No One Starts the Day Wanting to Do a Bad Job – Getting to Our Best Days Through Critical Thinking, Feedback, and Innovation”
Chief of Education and Academic Affairs for the American College of Obstetricians and Gynecologists (ACOG)
About Dr. Connolly
Dr. Connolly obtained her MD from Tufts University. After completing her residency in OBGYN at the University of North Carolina (UNC), she worked as a specialist in private practice for 2 years. She then returned to UNC and completed a fellowship in Urogynecology/Reconstructive Pelvic Surgery. Dr. Connolly continued her career at UNC where she was named the Annie Louise Wilkerson, MD ’36 Distinguished Professor, served as the Obstetrics and Gynecology clerkship director for 7 years, Residency Program Director for 11 years, the Fellowship Program Director for the Female Pelvic Medicine and Reconstructive Surgery Fellowship for 4 years and was also the Vice Chair for Education in the department of OBGYN. She is now the chief of education and academic affairs of ACOG.
While her clinical experience focused on urogynecology, her primary academic interests include medical education and the effect of childbirth on the pelvic floor. She has published original research on educational and clinical programming and tool development.
Her commitment to clinical practice and medical education has been recognized by the UNC School of Medicine. This includes her Directorship of the UNC Teaching Scholars Program for the past 13 years. Dr. Connolly has been honored for her educational efforts with multiple awards throughout her career at UNC. She is nationally recognized for her leadership in medical education.
Learn more about the E. James Aiman, MD, Endowed Lectureship
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Featuring The Roland S. Cron Lectureship
Guest Speaker
Kristyn Melíssa Brandi, MD, MPH
Board Chair
Physicians for Reproductive Health
About Dr. Brandi
Dr. Kristyn Brandi (pronouns: she/her/ella) is an Assistant Professor at Rutgers – New Jersey Medical School, where she completed her medical school and residency. She completed a Family Planning Fellowship at Boston University where she also earned her Master’s in Public Health with a concentration in Health Law, Bioethics and Human Rights. Her research is on reproductive decision making, contraceptive coercion, and racism in reproductive health care. She serves as the Board Chair of Physicians for Reproductive Health, sits on several sub-committees for the Society of Family Planning and is a founding member of Centering Equity, Racial and Cultural Literacy in Family Planning (CERCL-FP). She proudly identifies as a Latina pansexual abortion provider.
Agenda
| Time | Activity |
|---|---|
| 7:15am | GRAB AND GO BREAKFAST |
| 7:45am | WELCOME & INTRODUCTIONS |
| 8:00am | Christine Livergood, MD, MFM Fellow Characterization of RhoBTB1, a PPARγ target gene, in the Placenta Mentors: Curt Sigmund, PhD & Jenn McIntosh, MD |
| 8:15am | Jordan Hauck, DO, R3 Risk of unplanned healthcare utilization in post-partum period for patients with hypertensive disorders of pregnancy Mentor: Anna Palatnik, MD |
| 8:30am | Leigh Mahlum, MD, R3 Factors associated with persistent hypertension at 1-year postpartum in patients with gestational hypertension or preeclampsia Mentor: Anna Palatnik, MD |
| 8:45am | Sarah Amherdt, MD, R3 Incidence of adverse pregnancy outcomes based on the degree of short interpregnancy interval in urban Milwaukee population Mentor: Anna Palatnik, MD |
| 9:00am | Zack Schoppen, MD, R3 What To Expect When You’re Expecting a Medical Student Mentor: Kate Dielentheis, MD |
| 9:15am | Steph Nguyen, MD, R3 Continuity of Care and Non-Urgent Health Care Utilization Mentors: Jessica Francis, MD & Stephen McAvoy, MD |
| 9:30am | BREAK |
| 9:45am | Alex Petrie, MD, R3 Evaluating the use and utility of a Weight Loss Clinic referral after surgical treatment of Endometrial Cancer Mentor: Erin Bishop, MD |
| 10:00am | Katie Pellino, MD, R3 Post-Discharge Opioid Prescribing After Cesarean: A Quality Improvement Initiative Mentor: Erika Peterson, MD |
| 10:15am | David Eggert, DO, R2 The Influence of Patient Education Level, Infertility Treatment, and Pregnancy and Breastfeeding Status on Perceptions of the COVID-19 Vaccine: A Mixed Methods Study Mentor: Stephanie Gunderson, MD |
| 10:30am | Rebecca Sigourney, MD, R2 Investigating the Impact of the Addition of a MIGS Surgeon on Surgical Volume of General OBGYNs Mentor: Ben Beran, MD |
| 10:45am | BREAK |
| 11:00am | The Roland S. Cron Lecture: Kristyn Melíssa Brandi, MD, MPH Title: "Who is in Control Here- Contraceptive Coercion and Reproductive Justice" |
Featured Speaker: Isabel C. Green, MD, MEHP
“Not Just SIM-antics: Maximizing Simulation for Surgical Skills”
About Dr. Green
Dr. Green completed her Obstetrics & Gynecology residency at John Hopkins University and fellowship in Minimally Invasive Gynecologic Surgery at Georgetown University-MedStar. She serves as the Associate Program Director for the OB/GYN residency program at Mayo Clinic and directs a transition to residency course in the Mayo Medical School. She is also the Fellowship Director for Minimally Invasive Gynecology and a consultant of Minimally Invasive Gynecologic Surgery and Gynecology at Mayo Clinic.
Her practice interests are in office hysteroscopy and also the management of abnormal uterine bleeding, cervical dysplasia and chronic pelvic pain. Since residency she has been engaged in undergraduate and graduate medical education, with a focus in surgical education. In 2017 she completed a Masters of Education in the Health Professions from Johns Hopkins University.
Learn more about the E. James Aiman, MD, Endowed Lectureship
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Presented by
Hallgeir Rui, MD, PhD
WBCS Endowed Professor of Breast Cancer Research
Vice Chair of Research, Department of Pathology
Director of MCW Tissue Bank
Associate Director of Shared Resources, MCW Cancer Center
Medical College of Wisconsin
About
Hallgeir Rui, MD, PhD is internationally recognized for his research on hormone signaling in breast cancer, and has a strong track record of leadership, mentoring and collaboration. He is the WBCS Endowed Professor of Breast Cancer Research at the Medical College of Wisconsin (MCW), with his primary appointment in the Department of Pathology, and a secondary appointment to the Department of Pharmacology & Toxicology. In addition, Dr. Rui serves as the Associate Director of Basic Science and Shared Resources at the MCW Cancer Center. With his past experience as a Program Leader and Shared Resource Director at the NCI-designated Sidney Kimmel Cancer Center at Thomas Jefferson University, Dr. Rui brings valuable experience to the MCW Cancer Center efforts toward NCI-designation. Dr. Rui serves on the Breast Cancer Translational Research Committee of NRG Oncology.
A central focus of hisresearch is on molecular profiling of solid tumors, with published track record in malignancies of the breast, pancreas, prostate, colon, head and neck and melanomas. Key areas of interest are therapy-relevant protein expression, including pathway-activation status and tumor immunology-related markers, with development of better predictive markers and improved personalized cancer care as the overarching goal. Efforts are dedicated to improving methods and applications for quantitative, multiplex immunohistochemistry (IHC) for single-cell protein marker analyses – histocytometry – in solid tumors.
His laboratory invented novel ultrahigh density tissue arraying technology termed cutting-edge matrix assembly (CEMA) that overcomes limitations of core-based tissue arrays (US patent 8,349,584). Our laboratory, in collaboration with Dr. Kay-Uwe Wagner, developed novel prolactin-humanized NSG-Pro mouse strain for more accurate modeling and drug response testing of human breast cancer and other prolactin receptor-positive cancers, and my team has established a panel of new patient-derived breast cancer xenograft models in NSG-Pro mice.
Dr. Rui has extensive experience in facilitating multidisciplinary and collaborative program projects, including a concluded $6.7 million Promise Project Award funded by Susan G. Komen Foundation. Attesting to the productive use of immunofluorescence-based quantitative histocytometry and tissue arraying technologies for high-throughput application of innovative and nonstandard technologies for immunoprofiling of solid tumors, I led a multidisciplinary team that quantified levels of more than 100 therapy-relevant protein markers in nearly 3,000 breast cancer specimens, using tissue arrays and accompanying clinical data assembled and procured by a consortium of five institutions. As the leader of this consortium, I coordinated extensive efforts to combine tissue resources, data, equipment resources and broad areas of expertise.
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Presented by
Victor Jin, PhD
Linda T. and John A. Mellowes Endowed Chair of Bioinformatics and Data Analytics
Director, Bioinformatics Shared Resources
Professor, Institute for Health and Equity/Biostatistics
Medical College of Wisconsin
About
Dr. Jin has extensive experience in developing computational and genomics approaches for analyzing various omics-seq data, and runs a systems biology lab with a balanced dry and wet components.
Research Interests:
1) Developing genomics and computational approaches for the identification of three-dimensional (3D) chromatin interactions from the various omics-seq data.
2) Functionally and mechanistically characterizing the roles of epigenetic marks in cancer development and progression using novel techniques such as 3C/ChIP/RT-qPCR, 3D-FISH and CRISPR/Cas9.
3) Adapting/applying genome-wide omics-seq techniques in patient tissues to identify epigenetic-driven therapeutic targets and biomarkers.
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Featured Speaker: Serena H. Chan, MD, FACOG – “Gynecologic Surgery in Pediatric/Adolescent Patients: Special Considerations & Management of Mullerian Anomalies”
About Dr. Chan
Serena H. Chan, MD, FACOG, is Chief of the Pediatric & Adolescent Gynecology division at UPMC Children’s Hospital of Pittsburgh. She is also an Assistant Professor of Obstetrics, Gynecology & Reproductive Sciences at the University of Pittsburgh School of Medicine. She is board-certified in obstetrics and gynecology by the American Board of Obstetrics and Gynecology.
Dr. Chan earned her Medical Degree from Oregon Health and Science University before completing her Residency in Obstetrics and Gynecology at UPMC Magee-Womens Hospital. She also completed a Fellowship in Pediatric and Adolescent Gynecology Fellowship at Cincinnati Children’s Hospital.
Dr. Chan’s clinical specialties include medical and surgical management of pediatric and adolescent gynecologic concerns, congenital abnormalities of the female reproductive tract, and fertility preservation and reproductive endocrine issues in girls undergoing gonadotoxic therapy. Her research interests include gynecological concerns in females with anorectal malformations, trainee education in provision of adolescent reproduction health services. She has published and presented on the topics of surgical management of reproductive tract anomalies, fertility preservation, and gynecologic concerns in adolescent/young adult cancer survivors. She is a member of the North American Society for Pediatric/Adolescent Gynecology (NASPAG), the American Society for Reproductive Medicine (ASRM), the American Association of Gynecologic Laparoscopists (AAGL), and the American College of Obstetricians and Gynecologists (ACOG).
Register via Zoom for those not able to attend in person
Learn more about the E. James Aiman, MD, Endowed Lectureship[/vc_column_text][/vc_column][/vc_row]
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Schedule:
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| Time | Activity |
|---|---|
| 7:15am | BREAKFAST |
| 7:45am | WELCOME & INTRODUCTIONS |
| 8:00am | Yiwen Cui, MD, MFM Fellow O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes Mentor: Stephanie Olivier-Van Stichelen, PhD |
| 8:15am | Lindsay McAlarnen, MD GYN ONC Fellow Exosomal FXR1 as a translational mediator in the ovarian cancer microenvironment Mentor:Pradeep Chaluvally-Raghavan, PhD |
| 8:30am | Rebekah Summey, MD GYN ONC Fellow Exploration and exploitation of hormonal pathways in adult granulosa cell tumors for development of targeted therapeutics Mentors: Elizabeth Hopp, MD and Janet S. Rader, MD |
| 8:45am | Alex Levy, MD, R4 Is One Superior? Comparison of Early Removal Rates of Intrauterine Device versus Nexplanon Subdermal Implant in Women Ages 16-24 in Milwaukee, Wisconsin Mentor: Jessica Francis, MD |
| 9:00am | Rana Aliani, MD R3 Impact of Race, Insurance, and Procedural Timing on Sterilization Method Mentor: Ben Beran, MD |
| 9:15am | Mary Siracusa, MD R3 Determining Patients’ Preferred Ultrasound Provider During the Preoperative Evaluation of Endometriosis Mentor: Ben Beran, MD |
| 9:30am | BREAK |
| 9:45am | Iman Khan, MD R3 Postpartum Care in a Post-COVID Era Mentors: Amy Domeyer, MD and Erika Peterson, MD |
| 10:00am | Blake Neuburg, MD R3 Inpatient Versus Outpatient Management of Gestational Hypertension or Preeclampsia Without Severe Features Mentor: Anna Palatnik, MD |
| 10:15am | Ankita Sarawagi, MD R3 Screening rates for intimate partner violence (IPV) in the OBGYN clinic from 2019 to 2022 Mentor: Kim Gecsi, MD |
| 10:30am | Margaret Bruce, MD R3 Evaluating Modern Contraceptive Methods as Risk Factors for Recurrent UTI’s Mentor: Sumana Koduri, MD |
| 10:45am | BREAK |
| 11:00am | The Roland S. Cron Lecture: Nandini Raghuraman, MD, MS Fellowship Program Director, Maternal-Fetal Medicine Assistant Professor, OB/GYN Washington University School of Medicine "Moving Evidence into Clinical Practice on Labor & Delivery" |
| 12:00pm | Questions for Dr. Raghuraman |
| 12:30pm | Lunch |
Featuring The Roland S. Cron Lectureship
Guest Speaker
Nandini Raghuraman, MD MSCI
Fellowship Program Director, Maternal-Fetal Medicine
Assistant Professor, OB/GYN
Washington University School of Medicine
About Dr. Raghuraman
Nandini Raghuraman, MD, MSCI, is an Assistant Professor in the Division of Maternal-Fetal Medicine at Washington University in St Louis and the MFM Fellowship Program Director. She is a NIH-funded physician scientist with expertise in Labor & Delivery clinical trials and implementation science in obstetrics. She has authored over 70 peer reviewed manuscripts and is currently leading a multicenter randomized trial investigating the effect of maternal oxygen supplementation in labor for fetal resuscitation.
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Presented by
Wei Xu, PhD
Professor of Oncology, Marian A. Messerschmidt
Associate Director,, McArdle Laboratory for Cancer Research
Director of MCW Tissue Bank
Co-Director, Genetic and Epigenetic Mechanism Program, Carbone Cancer Center
About
Dr. Xu’s laboratory explores the protective roles of environmental and nutritional estrogenic compounds in mammals for breast cancer prevention and treatment. Estrogen receptors (ERs) exist in two forms, ERa and ERb, which have opposing roles in cell proliferation. Estrogenic compounds can control balance between mammary cell proliferation and differentiation via stimulating the formation of different forms of ER dimers. Xu lab has developed the Bioluminescent Resonance Energy Transfer (BRET) assays for detecting in vivo homodimerization and heterodimerization of ERa and ERb induced by estrogenic compounds. Biological functions of these estrogenic compounds are currently being investigated in cell-based and breast cancer mouse models. Dr. Xu’s laboratory has also employed biochemical and functional genomic approaches, as well as mouse genetics to decipher the contribution of histone arginine methylation to the epigenetic control of cancer cells. The major focus of Xu lab is on a protein arginine (R) methyltransferase CARM1/PRMT4, a nuclear hormone receptor co-activator. Dr. Xu has identified a number of non-histone substrates for CARM1 and is in the progress of elucidating the functions of protein arginine methylation in breast cancer initiation and progression.
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Featured Speaker: George B. Mychaliska, MD – “Leveraging Intrauterine Physiology – Fetal Surgery and the Artificial Placenta”
George B. Mychaliska, MD
Professor, Pediatric Surgery, Surgery
University of Michigan Health
George B. Mychaliska, M.D. is the Robert Bartlett, MD Collegiate Professor of Pediatric Surgery and a Professor of Obstetrics and Gynecology at the University of Michigan. He earned his Medical Degree and Master’s of Science from the Joint Medical Program at the University of California at San Francisco and Berkeley. He completed his General Surgery residency and Fetal Surgery fellowship at UCSF. Dr. Mychaliska completed his Pediatric Surgery fellowship at the Children’s Hospital of Michigan. He is board certified in Pediatric Surgery and General Surgery. Dr. Mychaliska’s practice encompasses all aspects of pediatric surgery. His clinical areas of interest and expertise are prenatal diagnosis and fetal surgery. Dr. Mychaliska’s research interests include prenatal diagnosis and therapy, pulmonary development, and congenital diaphragmatic hernia.[/vc_column_text][/vc_column][/vc_row]
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Presented by
Bo Wang, PhD
Director – Tissue Regenerative Engineering Laboratory (TRE Lab)
Assistant Professor – Department of Biomedical Engineering, The Marquette University and Medical College of Wisconsin
About
Dr. Bo Wang, Director and Principal Investigator of the TRE Lab, received her PhD in Biomedical Engineering from Mississippi State University in 2012 and completed her Postdoctoral Fellowship at Northwestern University’s Feinberg School of Medicine, Department of Surgery, in 2016. She joined the Marquette-MCW Joint Department of Biomedical Engineering in January of 2019 with research interests that include stem cell engineering, hard-tissue engineering and 3D bioprinting, as well as vascular tissue engineering, imaging, modeling and simulation.
The Tissue Regenerative Engineering Laboratory is developing bio-functional engineered tissues that provide advanced therapeutic options for such conditions as birth defects, bone disorders, and liver and vascular diseases. To do this, the TRE Lab will first develop a greater understanding of the biological and molecular processes involved in regenerative regression.
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Presented by
Navonil De Sarkar, PhD
Assistant Professor – Department of Pathology at the Medical College of Wisconsin
About
Navonil De Sarkar is an Assistant Professor at the Medical College of Wisconsin Cancer Center with a dual background in computational and experimental genomics; he brings a multidisciplinary approach to studying human cancers. His research focuses on understanding the natural history of the disease, devising noninvasive approaches to track adaptive and molecular evolutionary changes in cancer accurately, and ultimately developing practical strategies for precision medicine in advanced cancer patients (Augmented precision medicine).
Navonil received his Ph.D. from the Indian Statistical Institute and joined Peter Nelson’s lab at the University of Washington & Fred Hutchinson Cancer Research Center, Seattle, for postdoctoral training. Through adopting integrative genomics approaches, Navonil developed extensive experience analyzing tumor genomes to study functionally relevant mutations and structural aberrations using tumor tissue and circulating tumor DNA (ctDNA). Navonil participated in several large-scale consortium data analyses, including Stat-up-to-cancer germline and prostate tumor analysis efforts. Navonil led the bioinformatics analysis of the large-scale germline sequence work that highlighted the importance of inherited DNA repair genes in shaping the fate of advanced prostate cancer. He is one of the early discoverers of CDK12 loss-associated tandem duplicator signature. Subsequently, De Sarkar developed a machine learning-based classifier that accurately predicts functional homologous recombination deficiency. Recently, he co-led a study interrogating whole genomes of advanced prostate cancers using cell-free DNA sequencing and discovered imprints of cancer epigenomes in native cell-free DNA sequence data.
Navonil is a recipient of several trainee awards. To mention in 2019 Navonil received the very competitive Prostate Cancer Foundation Young Investigator Award. Then onwards, Navonil is co-leading Prostate Cancer Foundation DNA repair-focused working group activities. He is the editorial board member for Translational Oncology and an associate editor for the Genitourinary Oncology edition of Frontiers journals.
Navonil re-joined MCW in March 2023 and committed to establishing a multidisciplinary research group to develop cutting-edge but practical precision medicine tools for prostate and other cancers. Building on strong biological fundamentals and detailed understandings of the disease, De Sarkar Lab (DeTAnomics Lab) is developing novel therapeutic strategies and working to co-develop new genomic assays and computational genomics tools to help us tackle the most lethal types of prostate and other cancers. DeTAnomics Lab adopts long-read genomic sequencing techniques to better understand cancer genome, transcriptome, and epigenome. In the lab, DeTAnomics lab explores the complex interplay between the genome and epigenome to uncover new insights that can lead to the development of more effective therapeutics and biomarkers. Currently, DeSarkar and his team are working on developing a practical strategy to degrade BRCA2 in tumor cells so as to confer DNA-damaging mediated therapy benefits to a wider pool of patients.
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Featured Speaker: Sloane L. York, MD, MPH – “Reconsidering Abortion Training Post-Dobbs: Why is this integral to OBGYN education?”
About Dr. Chan
Sloane L. York, MD MPH, (she/her), is currently an Associate Professor of Obstetrics and Gynecology division of Complex Family Planning at Rush University Medical Center in Chicago, IL. She completed her residency in OBGYN in 2011 and Family Planning Fellowship in 2013 at Northwestern University, where she also received a Masters in Public Health. Dr. York joined the faculty at Rush in 2013 where she established family planning services and helped develop the Division of Family Planning. Since 2018, she has been the OBGYN Residency Program Director at Rush. Dr. York is also the Associate Program Director for the Complex Family Planning Fellowship at Rush which began in 2022. Additionally, she works as an OB Hospitalist at Rush and is a mom to two very active children.
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