Calendar of Events

Nov
12
Tue
2019
Breastfeeding: Beyond the Basics with Sarah Mess, CNM @ Moorland Reserve Health Center
Nov 12 @ 6:00 pm – 7:00 pm

When significant breastfeeding challenges are expected or met, creating a plan ahead of time can reduce stress and improve the breastfeeding experience

Presentation by: Sarah Mess, CNM.

Register online by going to Froedtert Health’s Classes and Events

Nov
13
Wed
2019
Developing Novel Biomarkers and Therapies Against Ovarian Cancer – Manish Patankar, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Nov 13 @ 12:00 pm – 1:00 pm

Presented by

Manish Patankar, PhD
Professor, Obstetrics & Gynecology, Division of Reproductive Sciences
Associate Director, Endocrine and Reproductive Physiology (ERP) Program
University of Wisconsin-Madison, School of Medicine and Public Health

About

Dr. Manish Patankar is a Professor in the Division of Reproductive Sciences. Dr. Patankar grew up in Thane, India, a city that borders Mumbai (Bombay). His wife is a physical therapist at the American Family Children’s Hospital and they have a 7 year old daughter who is in first grade at Glenn Stephens Elementary.

Dr. Patankar graduated from the University of Bombay, India with a B.S. in Chemistry in 1987. Subsequently, he received his Masters of Science in Organic Chemistry from the University of Bombay in 1990, and his Masters of Chemistry from Old Dominion University in Norfolk, Virginia in 1993. Dr. Patankar then completed his PhD in Biomedical Sciences at Eastern Virginia Medical School/Old Dominion University in 1998.

Dr. Patankar was an instructor and Research Professor at Eastern Virginia Medical School until 2004 when he joined the department as Professor and also became a member of the UW-Madison Carbone Cancer Center. His current research includes developing diagnostic tests for ovarian cancer and preeclampsia and strategies for treating ovarian cancer.

Collaborations at UW-Madison include: Drs. Joseph Connor, David Abbott, Paul Sondel, David Beebe, Ralph Albrecht, Mark Cook, Sean Fain, Ian Rowland, Hirak Basu and and Lingjun Li. Non UW-Madison collaborations include: Drs. Mitchell Ho and Ira Pastan (National Cancer Institute), Dr. Jennifer Gubbels (Augustana College, SD), Rebecca Whelan (Oberlin College, OH), Biotech Industry: Neoclone Biotechnology (Madison), and Gentel Biosciences (Fitchburg).

Dr. Patankar teaches Endocrine Physiology, Biology 151, and lectures on immunology in several different courses on campus.

What does he do in this spare time? He loves music and watching SpongeBob with his daughter.

One of the most interesting places that Dr. Patankar has visited is Bergen, Norway.

Research Focus

The primary focus of my research is to devise specific methods for early diagnosis of epithelial ovarian cancer (EOC) and to understand the effect of factors produced by ovarian tumors on the functional capacity of tumor infiltrating lymphocytes. This research involves extensive utilization of glycoproteomic analysis in conjunction with cellular immunology, molecular biology and glycobiology.

Learn more about the WHRP Seminars

Dec
12
Thu
2019
Anxiety in Women: Healthy Ways to Respond with Abbey Kruper, PsyD @ Froedtert Menomonee Falls Hospital
Dec 12 @ 6:00 pm – 7:00 pm

Learn basic information about how anxiety can present in women and develop strategies to manage distress in order to have a fuller life.

Presentation by: Abbey Kruper, PsyD, psychologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Dec
18
Wed
2019
Investigating Sugars and Artificial Sweeteners Exposure in Pregnancy and Lactation – Stephanie Olivier-Van Stichelen, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Dec 18 @ 12:00 pm – 1:00 pm

Presented by

Stephanie Olivier-Van Stichelen, PhD
Assistant Professor, Biochemistry
Medical College of Wisconsin

About

Dr. Olivier-Van Stichelen received her PhD degree in Biochemistry from the University of Lille, France in 2012. Her work was focused on the understanding of the nutrient-sensing O-GlcNAcylation in colorectal cancer development with a special interest in diet-dependent modification of the oncogene beta-catenin.

After completion of her degree, she was appointed as a post-doctoral Fellow in the Laboratory of Cellular and Molecular Biology at the National Institute of Health, Bethesda, MD, USA. In this lab, Dr. Olivier-Van Stichelen worked on different aspects of O-GlcNAcylation during development including X-inactivation of the O-GlcNAc Transferase gene. She also developed a brain O-GlcNAcase knockout model and studied the impact of sugar consumption during pregnancy on O-GlcNAc-dependent development of metabolic homeostasis. More recently, she developed interests in understanding the importance of artificial sweeteners for offspring’s metabolism and microbiome.

Dr. Olivier-Van Stichelen established her lab at the Medical College of Wisconsin at the crossroad of sweeteners, pregnancy, development and metabolism.

Research Focus

Due to the global trend of growing sweetener consumption, determining the interplay between diet and pre- and post-natal development is emerging as a critical area for research. Currently, the average American eats around 22 teaspoons of added sugar every day (30 sugar cubes/day hidden in foods). This modern glucose-rich diet correlates with an increase in the prevalence of obesity, diabetes and others metabolic syndromes. Moreover, the effort to reduce sugar consumption has led people to consume more non-caloric sweeteners (Aspartame, Sucralose, Acesulfame-K…). While they appear healthier for glucose homeostasis than a high carbohydrate diet, recent studies have shown that artificial sweeteners impact glucose metabolism as well as gut microbiota, rising questions about their excessive use.

Therefore, understanding what happens when caloric and non-caloric sweeteners are metabolized is of utmost importance for public health and the focus of my research group.

Nutrient-dependent O-GlcNAc cycling in development and disease

O-GlcNAcylation is one of the key components of diet-responsive signaling. This unique glucose rheostat is a ubiquitous and dynamic glycosylation of intracellular proteins with approximately 1000 modified proteins described to date. Two key enzymes drive O-GlcNAc cycling: The O-GlcNAc transferase (OGT) adds the modification and the O-GlcNAcase (OGA) removes it. Although many studies have focused on the decrease or complete absence of O-GlcNAc cycling by modulating the expression or activity of OGT, only a few studies have targeted hyper-O-GlcNAcylation by disturbing OGA. Because this post-translational modification is directly dependent on glucose input, depleting OGA creates an artificial and constant hyperglycemia-induced O-GlcNAcylation state. Using Oga and Ogt knockout (KO) cellular and mouse models, we can decipher the impact of high carbohydrate diet on embryonic development.

Non-Nutritive Sweeteners in pregnancy and lactation

Part of my lab is interested in understanding the impact of Non-Nutritive Sweetener (NNS) consumption through pregnancy and lactation. Although, NNS have been found in mother’s milk and in placental blood circulation, no study has focused on the fundamental effect of those non-caloric sweeteners on the developing organism.

Among the impacts described in adults are changes in intestinal hormonal secretion, glucose metabolism and most fascinating, re- duction of the gut microbiota. Nevertheless, the fundamental mechanisms of those changes are far from understood. Glycoproteins found on the surface of the intestinal epithelium define the glycocalyx and are an essential mammalian mechanism of communication with the gut microbiome. Their reciprocal relationship with the gut microbiome regulates not only nutrient breakdown, and food absorption, but also infection. We are convinced that by altering both microbiome and the detoxification process, NNS exposure in early life will impact metabolic homeostasis later in life.

Learn more about the WHRP Seminars

Jan
15
Wed
2020
Alcohol-Induced Developmental Brain Injury – Xiaowen Bai, MD, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Jan 15 @ 12:00 pm – 1:00 pm

Presented by

Xiaowen Bai, MD, PhD

Xiaowen Bai, MD, PhD

Xiaowen Bai, MD, PhD
Associate Professor, Cell Biology, Neurobiology & Anatomy
Medical College of Wisconsin

About

Dr. Bai’s research interests are centered on the application of stem cells on disease modeling and tissue regeneration. The current major focus of the laboratory is to utilize gain- and loss-of-function approaches to examine the novel molecular mechanisms underlying the roles of non-coding RNAs, mitochondria, and genetic factors in neurodegeneration and cardiotoxicity in mice, and translate the findings to humans using stem cell-derived brain cells, heart cells, three-dimensional mini brains, and heart organoids.

Research Area 1:

Non-coding RNAs, mitochondria, and cell stress-related genes in neurodegeneration:
Neurological disorders have emerged as a predominant healthcare concern in recent years due to their severe consequences on quality of life and prevalence throughout the world. Understanding the underlying mechanisms of these diseases and the interactions between different brain cell types is essential for the development of new therapeutics. Many drugs (e.g., anesthetics), environmental factors (e.g., alcohol), diseases, and genetic risks are related to neurodegeneration. We examine the novel molecular mechanisms underlying the roles of microRNAs, long non-coding RNAs, mitochondria, immediate early and other cell stress-related genes in neurodegeneration using both mouse, and human stem cell-derived brain cell and three-dimensional mini brain models

Research Area 2:

Stem cell-mediated myocardial regeneration
Myocardial infarction is one of the major causes of death throughout the world. Currently, there is not a highly effective approach for treatment. Stem cells hold promise in repairing injured cardiac tissue. Our lab is involved in studying the effect of the transplantation of adipose tissue-derived stem cells and induced pluripotent stem cell-derived cardiomyocytes on myocardial regeneration following ischemia injury. A molecular imaging method has been developed to investigate the molecular mechanisms controlling homing, engraftment, and survival of injected cells in vivo.

Research Area 3:

The mechanisms of impaired cardioprotection under diabetic conditions
Hyperglycemia has been shown to be particularly detrimental to the cardioprotective effects, with the underlying mechanisms remaining largely unknown. We have developed and validated a clinically relevant model of functional human cardiomyocytes derived from both normal induced pluripotent stem cells (iPSCs) and diabetes mellitus iPSCs. This in vitro model of human disease will enable developmental and comparative studies of normal and diabetic cardiomyocytes to address genetic and environmental mechanisms responsible for attenuation of cardioprotection signaling in diabetics.

Learn more about the WHRP Seminars

Feb
3
Mon
2020
Taking Control of Your Bladder with Emily Davidson, MD @ Froedtert Fitness Center, Wauwatosa
Feb 3 @ 6:00 pm – 7:00 pm

Urinary issues including urgency and leakage are not something you should have to live with or schedule your life around. Learn about types of leakage and the options that exist for treatment.

Presentation by: Emily Davidson, MD, Urogynecologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Feb
6
Thu
2020
Does My Diet Affect Getting Pregnant? with Carol Eling, APNP @ Froedtert Drexel Town Square Health Center
Feb 6 @ 6:00 pm – 7:00 pm

We will take a look at the latest research on reproductive nutrition to improve your chances of conceiving.

Presentation by: Carol A. Eling, Advanced Practice Nurse Practitioner

Register Online

Register online through the link to Froedtert’s classes and events below.

Feb
19
Wed
2020
Analysis of Collagen Alterations in Human Ovarian Cancer by High Resolution Optical Microscopy – Paul Campagnola, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Feb 19 @ 12:00 pm – 1:00 pm

Presented by

Paul Campagnola, PhD
Professor, Biomedical Engineering
University of Wisconsin-Madison

About

Campagnola’s research is directed toward developing high resolution imaging modalities. The technologies his group has developed can readily be applied to problems in eye and vision research. For example, the technique of Second Harmonic Generation (SHG) to image collagen fibrillar structure has been used by other labs to image the corneal structure. Expanding into eye research is a natural direction for the Campagnola Laboratory.

Alterations to the extracellular matrix (ECM) composition and structure are thought to be critical for tumor initiation and progression for several epithelial carcinomas, including those of the ovary and breast. Our lab develops Second Harmonic Generation (SHG) microscopy tools to quantitative assess these alterations in the stroma where we correlate the optical signatures with structural changes in the fibrillar assembly between normal and diseased tissues. This physical approach provides objective measurements that may be used to understand disease progression. To further investigate how remodeling enables invasion and metastasis in vivo we use multiphoton excited (MPE) photochemistry to fabricate biomimetic in vitro models of the ovarian ECM. The nano/microstructured models simulate the crosslinked fibrillar structure of the native ECM.

Tissue engineering has vast potential to improve human health by repair and maintenance of existing tissue or generation of replacement of tissues and organs. A major limitation has been an incomplete understanding of the underlying cell-ECM interactions that govern cell adhesion which will ultimately affect downstream functions. Our approach to this problem utilizes MPE photochemistry to create 3D biomimetic scaffolds directly from crosslinked proteins. Beginning with bio-inspired designs we will seek to achieve improved function.

Learn more about the WHRP Seminars

May
1
Fri
2020
Blood, Sweat and Tears – The Challenges of Hematologic Disorders in Pregnancy with Jennifer McIntosh, DO, MS @ Virtual WebEx - email below for link
May 1 @ 8:00 am – 9:00 am
Nov
9
Mon
2020
Family History in Cancer Screening and Treatment – Elizabeth Hopp, MD @ Virtual
Nov 9 @ 5:45 pm – 7:00 pm


Please join us virtually. This talk will detail what constitutes a significant family history along with discussion of genetic testing. The talk will also touch on management of hereditary cancer syndromes, such as Lynch syndrome and BRCA.

Presentation by: Elizabeth Hopp, MD, Gynecologic Oncologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Nov
10
Tue
2020
Anxiety in Women: Healthy Ways to Respond with Abbey Kruper, PsyD @ Virtual
Nov 10 @ 5:45 pm – 7:00 pm

Please join us virtually to learn basic information about how anxiety can present in women and develop strategies to manage distress in order to have a fuller life.

Presentation by: Abbey Kruper, PsyD, psychologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Nov
18
Wed
2020
Infertility: Fact or Fiction with Bo Rydze, MD @ Virtual
Nov 18 @ 5:45 pm – 7:00 pm


Please join us virtually! This talk is geared towards giving both individuals and couples the knowledge to make informed decisions about how to best go about building their families or preserving their fertility. During this time we will dispel common myths surrounding fertility and answer any questions you may have. We will also cover red flags that could mean a potential risk for infertility down the road.

Presentation by: Bo Rydze, MD, Reproductive Endocrinologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Dec
9
Wed
2020
How Does Preeclampsia Impact Your Pregnancy and Your Future Health with Jennifer Jury McIntosh, DO @ Virtual
Dec 9 @ 5:45 pm – 7:00 pm


Please join us virtually! We will discuss what preeclampsia is and the signs and symptoms to watch for in pregnancy, as well as how it’s managed.

We will also explain the impact of preeclampsia on a woman’s future heart health.

Presentation by: Jennifer Jury McIntosh, DO, Perinatologist

Register Online

Register online through the link to Froedtert’s classes and events below.

May
13
Thu
2021
Autoimmune Disorders and Fertility with Jayme Bosler, MD @ Virtual Event (register below)
May 13 @ 6:00 pm – 7:00 pm

Please join us virtually! Women with existing autoimmune diseases may be at higher risk of infertility and some autoimmune conditions can increase a woman’s risk of miscarriage.

Together we will discuss these conditions and what to do to increase your chances of a successful pregnancy.

We will also explain the impact of preeclampsia on a woman’s future heart health.

Presentation by: Jayme Bosler, MD, Reproductive Endocrinology and Infertility physician

Register Online

Register online through the link to Froedtert’s classes and events below.

May
19
Wed
2021
Patient Education Webinar: Urinary Incontinence with Dr. Emily Davidson @ Virtual Event (register below)
May 19 @ 12:00 pm – 1:00 pm

Urinary issues including urgency and leakage are not something you should have to live with or schedule your life around. Learn about types of leakage and the options that exist for treatment.

Presentation by: Emily Davidson, MD, Urogynecologist

Sep
11
Sat
2021
Black Birth: A Maternal Health Conversation and Resource Fair @ Wisconsin Black Historical Society
Sep 11 @ 11:00 am – 1:00 pm


The Milwaukee Film Festival and Froedtert & the Medical College of Wisconsin present Black Birth: A Maternal Health Conversation and Resource Fair.

The short film Black Birth serves as the backdrop to a community dialogue about the joys, fears, complexities, and disparities of Black motherhood in America and locally in Milwaukee. Following the film screening will be a panel discussion including an OB-GYN physician and resident, community doula, African American breastfeeding expert, and other maternal-fetal care specialists, as well as a resource fair featuring leading health and wellness community partners.


This in-person event is FREE and open to the public. Space is limited to the first 150 people. Masks are REQUIRED and will be provided if needed. There is no virtual option. No Tickets required.

TimeTopic
11:00 AMWelcome and Introduction
11:15 AMShort Film
11:45 AM Discussion
12:15 - 1:00 PMPanel Questions and Discussion

Panelists

  • Moderator: Amy Domeyer-Klenske, MD – Obstetrician and Gynecologist
  • OBGYN Providers: Seema Menon, MD – Obstetrician and Gynecologist and Ciera Oshodi, MD – OBGYN Resident
  • Breastfeeding Expert: Dalvery Blackwell, BA, IBCLC with the African American Breastfeeding Network I
  • Doula
  • Patient
Oct
21
Thu
2021
Professionalism Week 2021: Navigating Pandexit – Rebounding from Individual and Collective Challenges @ Virtual Event (register below)
Oct 21 @ 9:00 am – 10:00 am
Professionalism Week 2021: Navigating Pandexit - Rebounding from Individual and Collective Challenges @ Virtual Event (register below)

Please join us as we discuss how groups can successfully navigate collective trauma with the COVID-19 pandemic as a model. It is how we cultivate resilience as a group, foster communication and individually and collectively recover and grow that determines whether an initial trauma will cause additional fall out. We propose to review some best practices for how to collectively navigate “pandexit” or recovery from any traumatic or stressful situation that affects a large group of people. In this session, we will discuss individual and group tools for resilience, go over acute and chronic reactions to trauma and discuss how leadership can steer groups of people into recovery.

Speakers:

      Kate Dielentheis, MD, assistant professor of obstetrics and gynecology
      Kristy Graettinger, MD, associate professor of obstetrics and gynecology
      Abbey Kruper, PsyD, associate professor of obstetrics and gynecology, psychiatry and behavioral medicine