Calendar of Events

Oct
12
Wed
2022
2022 E. James Aiman Lecture: Isabel C. Green, MD, MEHP @ Medical College of Wisconsin - Alumni Center. Zoom available
Oct 12 @ 8:30 am – 9:30 am

Featured Speaker: Isabel C. Green, MD, MEHP

“Not Just SIM-antics: Maximizing Simulation for Surgical Skills”

About Dr. Green

Dr. Green completed her Obstetrics & Gynecology residency at John Hopkins University and fellowship in Minimally Invasive Gynecologic Surgery at Georgetown University-MedStar. She serves as the Associate Program Director for the OB/GYN residency program at Mayo Clinic and directs a transition to residency course in the Mayo Medical School. She is also the Fellowship Director for Minimally Invasive Gynecology and a consultant of Minimally Invasive Gynecologic Surgery and Gynecology at Mayo Clinic.

Her practice interests are in office hysteroscopy and also the management of abnormal uterine bleeding, cervical dysplasia and chronic pelvic pain. Since residency she has been engaged in undergraduate and graduate medical education, with a focus in surgical education. In 2017 she completed a Masters of Education in the Health Professions from Johns Hopkins University.

Register via Zoom

Learn more about the E. James Aiman, MD, Endowed Lectureship

Feb
22
Wed
2023
Precision Pathology and PDX Models for Breast Cancer Drug Response Prediction – Hallgeir Rui, MD, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Feb 22 @ 12:00 pm – 1:00 pm

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Presented by

Hallgeir Rui, MD, PhD
WBCS Endowed Professor of Breast Cancer Research
Vice Chair of Research, Department of Pathology
Director of MCW Tissue Bank
Associate Director of Shared Resources, MCW Cancer Center
Medical College of Wisconsin

About

Hallgeir Rui, MD, PhD is internationally recognized for his research on hormone signaling in breast cancer, and has a strong track record of leadership, mentoring and collaboration. He is the WBCS Endowed Professor of Breast Cancer Research at the Medical College of Wisconsin (MCW), with his primary appointment in the Department of Pathology, and a secondary appointment to the Department of Pharmacology & Toxicology. In addition, Dr. Rui serves as the Associate Director of Basic Science and Shared Resources at the MCW Cancer Center. With his past experience as a Program Leader and Shared Resource Director at the NCI-designated Sidney Kimmel Cancer Center at Thomas Jefferson University, Dr. Rui brings valuable experience to the MCW Cancer Center efforts toward NCI-designation. Dr. Rui serves on the Breast Cancer Translational Research Committee of NRG Oncology.

A central focus of hisresearch is on molecular profiling of solid tumors, with published track record in malignancies of the breast, pancreas, prostate, colon, head and neck and melanomas. Key areas of interest are therapy-relevant protein expression, including pathway-activation status and tumor immunology-related markers, with development of better predictive markers and improved personalized cancer care as the overarching goal. Efforts are dedicated to improving methods and applications for quantitative, multiplex immunohistochemistry (IHC) for single-cell protein marker analyses – histocytometry – in solid tumors.

His laboratory invented novel ultrahigh density tissue arraying technology termed cutting-edge matrix assembly (CEMA) that overcomes limitations of core-based tissue arrays (US patent 8,349,584). Our laboratory, in collaboration with Dr. Kay-Uwe Wagner, developed novel prolactin-humanized NSG-Pro mouse strain for more accurate modeling and drug response testing of human breast cancer and other prolactin receptor-positive cancers, and my team has established a panel of new patient-derived breast cancer xenograft models in NSG-Pro mice.

Dr. Rui has extensive experience in facilitating multidisciplinary and collaborative program projects, including a concluded $6.7 million Promise Project Award funded by Susan G. Komen Foundation. Attesting to the productive use of immunofluorescence-based quantitative histocytometry and tissue arraying technologies for high-throughput application of innovative and nonstandard technologies for immunoprofiling of solid tumors, I led a multidisciplinary team that quantified levels of more than 100 therapy-relevant protein markers in nearly 3,000 breast cancer specimens, using tissue arrays and accompanying clinical data assembled and procured by a consortium of five institutions. As the leader of this consortium, I coordinated extensive efforts to combine tissue resources, data, equipment resources and broad areas of expertise.

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Mar
11
Sat
2023
Below the Belt: an Endometriosis Movie Screening and Panelist Discussion Event @ Oriental Theatre
Mar 11 @ 3:00 pm – 5:00 pm

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Below the Belt is a movie that shows personal & inspiring stories of four patients urgently searching for answers to mysterious symptoms. It exposes widespread problems in our healthcare systems that disproportionately affect women, and especially women of color who are less likely to be believed, diagnosed & effectively treated for menstrual health issues.

Through the lens of endometriosis, a disease that affects 1 in 9 women/people, the film shows how women are often dismissed, discounted & disbelieved. From societal taboos and gender bias to misinformed doctors and profit-driven healthcare, the film reveals how millions are effectively silenced and how, by fighting back, they can improve healthcare for everyone.[/vc_column_text][vc_separator type=”normal” thickness=”3″][vc_empty_space height=”12px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column width=”2/3″][vc_column_text]Please join us for this free and personal viewing with a discussion and Q&A session with some of our experts. Please keep in mind this viewing is for ages 14+.[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”34965″ img_size=”full” style=”vc_box_border” onclick=”link_image” qode_css_animation=””][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column][vc_separator type=”normal” thickness=”3″][vc_column_text]

Our expert panelists:

[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column width=”1/4″][vc_single_image image=”31056″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Ben Beran, MD
Assistant Professor; Co-Director, Fibroid Clinic: Alternative to Hysterectomies[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”31064″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Camila Bomtempo, MD
Assistant Professor – Obstetrics & Gynecology[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35009″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Carrie Peterson, MD
Associate Professor – Colorectal Surgery[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35013″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Morgan Briggs, MD
Assistant Professor – Obstetrics & Gynecology[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column width=”1/4″][vc_single_image image=”35010″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Emorie Harty
Patient to share story[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35011″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Emily Vanderhoef
Patient to share story[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35034″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Brendalyn Ghazaly
Patient to share story[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”31064″ style=”vc_box_border_circle” qode_css_animation=”” el_class=”hide”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_separator type=”normal” thickness=”3″][vc_column_text]

Agenda:

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  • 3:00pm – Welcome and Introductions
  • 3:10pm – Movie Viewing
  • 4:05pm – Panelist Discussion and Q&As
  • 5:00pm – Conclusion

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Giving:

[/vc_column_text][vc_column_text]You can make a difference by supporting cutting-edge endometriosis research and widespread disease recognition and awareness:

· Call Meg Bilicki at (414) 955-4711 or[/vc_column_text][vc_column_text]

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Our expert panelists include:

Ben Beran, MD (obstetrician, gynecologist and co-director of our Fibroid Clinic), Camila Bomtempo, MD (obstetrician & gynecologist), Carrie Peterson, MD (a colorectal surgeon at MCW), and 2 patients willing to share their story – Emorie Harty and Emily Vanderhoef![/vc_column_text][/vc_column][/vc_row]

Apr
12
Wed
2023
2023 Eleanor Delfs Lecture: “Building and Sustaining Strong Interpersonal Relationships to create a Prism of Success” – Dr. Idahlynn Karre @ MCW Bolger Auditorium
Apr 12 @ 8:30 am – 9:30 am

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Featured Speaker: Idahlynn Karre, PhD – “Building and Sustaining Strong Interpersonal Relationships to create a Prism of Success”

CEO, Council for Healthcare Leadership
Denver, CO

Idahlynn has spent her career as a professor, leader, administrator, speaker, consultant, and coach. She has had an award-winning professional career as a university professor, scholar, and leader. For the past 30 years she has devoted her time and energy to professional speaking, writing, executive coaching, and consulting for healthcare, higher education, business, and professional associations in the US, Canada, Ireland, UK, Europe, Asia, China, and Australia. Her professional goal is to facilitate excellence in personal and professional growth by creating and facilitating innovative and highly interactive learning environments and opportunities for professionals and to develop knowledge, skill, and capacity for positive learning outcomes and achievement of excellence for individuals, teams, and organizations.

Dr. Karre (PhD. University of Colorado, 1975) has been recognized for excellence in teaching, speaking, research, and leadership. Repeatedly chosen as Favorite Professor by her university students (1969-2002), recognized as University Scholar, Woman of the Year, National Teacher of the Year (1992), International Leader of the Year (2000), Gallup Vision Award (2008), numerous citations from the Fortune 1000, and in 2011 honored by the International Leadership Academy as they named their annual award for leadership excellence in her name.

For over 50 years, Idahlynn has enjoyed designing and facilitating multi-session professional development management and leadership training for higher education and healthcare organizations. Her current clients include: The Society for Maternal Fetal Medicine; Sera Prognostics International Women’s Healthcare; HERA Women’s Health; State Colleges and Universities of New York, PEAKS (A Collaborative of New York Community Colleges), Harvard Medical School, Community Colleges of Minnesota, South Dakota School of Mines, University of Houston, University of California College and Universities, Colleges and Universities of Nova Scotia, Khesar Gyalpo University of Medical Sciences of Bhutan, National Maternity Hospital Dublin Ireland, Columbia University Medical School, New York City Mount Sinai Healthcare System, American College of Obstetrics and Gynecology, Association of Professors of Gynecology and Obstetrics, Obstetrics and Neonatal Nurses; Banner Health, and others.

As a contributor to professional publications her scholarship and authorship focuses on strengths-based leadership; positive psychology; creating and sustaining effective interpersonal relationships; building and coaching high performance teams; leading with influence; creating cultures of excellence; servant leadership; engaging in conversation that matter for personal, professional, and organization growth; feedback, crucial conversations, talent management, and professional accountability. She is a certified trainer with the Gallup Organization, StrengthsQuest, Crucial Learning (formerly VitalSmarts), DiSC, and Emotional Intelligence 2.0.

Register via Zoom for those not able to attend in person

Learn more about the Eleanor Delfs Lectureship for Pioneers[/vc_column_text][/vc_column][/vc_row]

Apr
21
Fri
2023
22nd Annual Women’s Health Conference – April 21, 2023 @ Potawatomi Hotel & Casino Event Center
Apr 21 @ 7:30 am – 5:00 pm

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The Annual Women’s Health Conference is a one-day CME accredited program through MCW, ACOG and AAFP, providing up-to-date information in all aspects of Women’s Health and medical updates in General OBGYN and subspecialties. While most conferences focus on the needs of our patients, we have taken an active approach to incorporate provider wellness. In recent years, we have featured topics such as provider burnout, self-care, and second victim. Some of our most popular topics have included contraception, sexual dysfunction and menopause.

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Guest Speaker – Lauren Streicher, MD:

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Clinical Professor of Obstetrics & Gynecology at Northwestern Medicine
Medical Director – Northwestern Medicine Center for Sexual Medicine and Menopause

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Educates women through consumer publications, media appearances, and writing books, such as:

  • Chicago’s WGN Morning News
  • The Today Show
  • The New York Times
  • Wall Street Journal
  • Women’s Health
  • Sex RX
  • Slip Sliding Away

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Speakers and Topics:

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Apr
26
Wed
2023
“Epigenetic Regulated Heterogeneity in Endocrine Resistant Breast Cancer” – Victor Jin, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Apr 26 @ 12:00 pm – 1:00 pm

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Presented by

Victor Jin, PhD
Linda T. and John A. Mellowes Endowed Chair of Bioinformatics and Data Analytics
Director, Bioinformatics Shared Resources
Professor, Institute for Health and Equity/Biostatistics
Medical College of Wisconsin

About

Dr. Jin has extensive experience in developing computational and genomics approaches for analyzing various omics-seq data, and runs a systems biology lab with a balanced dry and wet components.

Research Interests:

1) Developing genomics and computational approaches for the identification of three-dimensional (3D) chromatin interactions from the various omics-seq data.
2) Functionally and mechanistically characterizing the roles of epigenetic marks in cancer development and progression using novel techniques such as 3C/ChIP/RT-qPCR, 3D-FISH and CRISPR/Cas9.
3) Adapting/applying genome-wide omics-seq techniques in patient tissues to identify epigenetic-driven therapeutic targets and biomarkers.

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May
10
Wed
2023
2023 E. James Aiman Lecture: Serena H. Chan, MD, FACOG @ Medical College of Wisconsin - Bolger (previously HRC) Auditorium, Medical Education Building
May 10 @ 8:30 am – 9:30 am

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Featured Speaker: Serena H. Chan, MD, FACOG – “Gynecologic Surgery in Pediatric/Adolescent Patients: Special Considerations & Management of Mullerian Anomalies”

About Dr. Chan

Serena H. Chan, MD, FACOG, is Chief of the Pediatric & Adolescent Gynecology division at UPMC Children’s Hospital of Pittsburgh. She is also an Assistant Professor of Obstetrics, Gynecology & Reproductive Sciences at the University of Pittsburgh School of Medicine. She is board-certified in obstetrics and gynecology by the American Board of Obstetrics and Gynecology.

Dr. Chan earned her Medical Degree from Oregon Health and Science University before completing her Residency in Obstetrics and Gynecology at UPMC Magee-Womens Hospital. She also completed a Fellowship in Pediatric and Adolescent Gynecology Fellowship at Cincinnati Children’s Hospital.

Dr. Chan’s clinical specialties include medical and surgical management of pediatric and adolescent gynecologic concerns, congenital abnormalities of the female reproductive tract, and fertility preservation and reproductive endocrine issues in girls undergoing gonadotoxic therapy. Her research interests include gynecological concerns in females with anorectal malformations, trainee education in provision of adolescent reproduction health services. She has published and presented on the topics of surgical management of reproductive tract anomalies, fertility preservation, and gynecologic concerns in adolescent/young adult cancer survivors. She is a member of the North American Society for Pediatric/Adolescent Gynecology (NASPAG), the American Society for Reproductive Medicine (ASRM), the American Association of Gynecologic Laparoscopists (AAGL), and the American College of Obstetricians and Gynecologists (ACOG).

Register via Zoom for those not able to attend in person

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Jun
28
Wed
2023
2023 Resident and Fellow Research & Alumni Day @ In-person event only. Alumni Center, MCW Medical Education Building
Jun 28 @ 7:15 am – 1:30 pm

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Schedule:

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TimeActivity
7:15amBREAKFAST
7:45amWELCOME & INTRODUCTIONS
8:00amYiwen Cui, MD, MFM Fellow
O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes

Mentor: Stephanie Olivier-Van Stichelen, PhD
8:15amLindsay McAlarnen, MD GYN ONC Fellow
Exosomal FXR1 as a translational mediator in the ovarian cancer microenvironment

Mentor:Pradeep Chaluvally-Raghavan, PhD
8:30amRebekah Summey, MD GYN ONC Fellow
Exploration and exploitation of hormonal pathways in adult granulosa cell tumors for development of targeted therapeutics

Mentors: Elizabeth Hopp, MD and Janet S. Rader, MD
8:45amAlex Levy, MD, R4
Is One Superior? Comparison of Early Removal Rates of Intrauterine Device versus Nexplanon Subdermal Implant in Women Ages 16-24 in Milwaukee, Wisconsin

Mentor: Jessica Francis, MD
9:00amRana Aliani, MD R3
Impact of Race, Insurance, and Procedural Timing on Sterilization Method

Mentor: Ben Beran, MD
9:15amMary Siracusa, MD R3
Determining Patients’ Preferred Ultrasound Provider During the Preoperative Evaluation of Endometriosis

Mentor: Ben Beran, MD
9:30amBREAK
9:45amIman Khan, MD R3
Postpartum Care in a Post-COVID Era

Mentors: Amy Domeyer, MD and Erika Peterson, MD
10:00amBlake Neuburg, MD R3
Inpatient Versus Outpatient Management of Gestational Hypertension or Preeclampsia Without Severe Features

Mentor: Anna Palatnik, MD
10:15amAnkita Sarawagi, MD R3
Screening rates for intimate partner violence (IPV) in the OBGYN clinic from 2019 to 2022

Mentor: Kim Gecsi, MD
10:30amMargaret Bruce, MD R3
Evaluating Modern Contraceptive Methods as Risk Factors for Recurrent UTI’s


Mentor: Sumana Koduri, MD
10:45amBREAK
11:00amThe Roland S. Cron Lecture:
Nandini Raghuraman, MD, MS
Fellowship Program Director, Maternal-Fetal Medicine
Assistant Professor, OB/GYN
Washington University School of Medicine

"Moving Evidence into Clinical Practice on Labor & Delivery"
12:00pmQuestions for Dr. Raghuraman
12:30pmLunch
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Featuring The Roland S. Cron Lectureship

Guest Speaker

Nandini Raghuraman, MD MSCI
Fellowship Program Director, Maternal-Fetal Medicine
Assistant Professor, OB/GYN
Washington University School of Medicine

About Dr. Raghuraman

Nandini Raghuraman, MD, MSCI, is an Assistant Professor in the Division of Maternal-Fetal Medicine at Washington University in St Louis and the MFM Fellowship Program Director. She is a NIH-funded physician scientist with expertise in Labor & Delivery clinical trials and implementation science in obstetrics. She has authored over 70 peer reviewed manuscripts and is currently leading a multicenter randomized trial investigating the effect of maternal oxygen supplementation in labor for fetal resuscitation.

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Jul
26
Wed
2023
Protein Arginine Methylation: Mechanisms and Therapeutic Vulnerabilities – Wei Xu, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Jul 26 @ 12:00 pm – 1:00 pm

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Presented by

Wei Xu, PhD
Professor of Oncology, Marian A. Messerschmidt
Associate Director,, McArdle Laboratory for Cancer Research
Director of MCW Tissue Bank
Co-Director, Genetic and Epigenetic Mechanism Program, Carbone Cancer Center

About

Dr. Xu’s laboratory explores the protective roles of environmental and nutritional estrogenic compounds in mammals for breast cancer prevention and treatment. Estrogen receptors (ERs) exist in two forms, ERa and ERb, which have opposing roles in cell proliferation. Estrogenic compounds can control balance between mammary cell proliferation and differentiation via stimulating the formation of different forms of ER dimers. Xu lab has developed the Bioluminescent Resonance Energy Transfer (BRET) assays for detecting in vivo homodimerization and heterodimerization of ERa and ERb induced by estrogenic compounds. Biological functions of these estrogenic compounds are currently being investigated in cell-based and breast cancer mouse models. Dr. Xu’s laboratory has also employed biochemical and functional genomic approaches, as well as mouse genetics to decipher the contribution of histone arginine methylation to the epigenetic control of cancer cells. The major focus of Xu lab is on a protein arginine (R) methyltransferase CARM1/PRMT4, a nuclear hormone receptor co-activator. Dr. Xu has identified a number of non-histone substrates for CARM1 and is in the progress of elucidating the functions of protein arginine methylation in breast cancer initiation and progression.

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Sep
27
Wed
2023
2023 Annual Sterner Lecture for Fetal Medicine @ MCW Alumni Center
Sep 27 @ 8:30 am – 9:30 am

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Featured Speaker: George B. Mychaliska, MD – “Leveraging Intrauterine Physiology – Fetal Surgery and the Artificial Placenta”

George B. Mychaliska, MD

Professor, Pediatric Surgery, Surgery
University of Michigan Health

George B. Mychaliska, M.D. is the Robert Bartlett, MD Collegiate Professor of Pediatric Surgery and a Professor of Obstetrics and Gynecology at the University of Michigan. He earned his Medical Degree and Master’s of Science from the Joint Medical Program at the University of California at San Francisco and Berkeley. He completed his General Surgery residency and Fetal Surgery fellowship at UCSF. Dr. Mychaliska completed his Pediatric Surgery fellowship at the Children’s Hospital of Michigan. He is board certified in Pediatric Surgery and General Surgery. Dr. Mychaliska’s practice encompasses all aspects of pediatric surgery. His clinical areas of interest and expertise are prenatal diagnosis and fetal surgery. Dr. Mychaliska’s research interests include prenatal diagnosis and therapy, pulmonary development, and congenital diaphragmatic hernia.[/vc_column_text][/vc_column][/vc_row]

Application of Human Amniotic Membrane in Tissue Engineering – Bo Wang, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Sep 27 @ 12:00 pm – 1:00 pm

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Presented by

Bo Wang, PhD
Director – Tissue Regenerative Engineering Laboratory (TRE Lab)
Assistant Professor – Department of Biomedical Engineering, The Marquette University and Medical College of Wisconsin

About

Dr. Bo Wang, Director and Principal Investigator of the TRE Lab, received her PhD in Biomedical Engineering from Mississippi State University in 2012 and completed her Postdoctoral Fellowship at Northwestern University’s Feinberg School of Medicine, Department of Surgery, in 2016. She joined the Marquette-MCW Joint Department of Biomedical Engineering in January of 2019 with research interests that include stem cell engineering, hard-tissue engineering and 3D bioprinting, as well as vascular tissue engineering, imaging, modeling and simulation.

The Tissue Regenerative Engineering Laboratory is developing bio-functional engineered tissues that provide advanced therapeutic options for such conditions as birth defects, bone disorders, and liver and vascular diseases. To do this, the TRE Lab will first develop a greater understanding of the biological and molecular processes involved in regenerative regression.

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Oct
11
Wed
2023
2023 Eleanor Delfs Lecture: “Women’s Health from Molecule to Market” – Dr. Kelle Moley @ MCW Alumni Center
Oct 11 @ 8:30 am – 9:30 am

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Featured Speaker: Kelle Moley, MD – “Women’s Health from Molecule to Market”

Dr. Kelle Moley is a career physician-scientist obstetrician/gynecologist who currently leads the Reproductive Health Technologies Domain within the Discovery & Translational Sciences, Global Health Division at the Bill and Melinda Gates Foundation. Kelle joined BMGF in July 2020, with a 30-year history of basic and translational research on reproductive health issues in females throughout the life course– from organismal to cellular and molecular levels of metabolic, developmental biology, embryo implantation and decidualization, and infectious diseases of the female reproductive tract.

Kelle earned her BA from Wellesley College, and her MD from Yale Medical School. Thereafter, she pursued an Obstetrics & Gynecology Residency and a Fellowship in Reproductive Endocrinology & Fertility at Washington University in St. Louis School of Medicine. Kelle then spent the next 3 decades of a thriving research career at Washington University—rising to become the James P. Crane Professor of Obstetrics & Gynecology, Vice Chair of Obstetrics & Gynecology, Chief of the Division of Basic & Translational Research for the Department of Obstetrics & Gynecology, Co-Director of the Institute of Clinical & Translational Science for the School of Medicine, and Director of the Center for Reproductive Health Sciences at the School of Medicine. Her research (published in some 150 peer-reviewed primary articles) led to an international reputation along with numerous honors, including election to the National Academy of Medicine in 2014. She also earned a reputation as a superb mentor to trainees, leading the reproductive endocrinology fellowship program at Washington University until she left academia in 2018. After a 2-year stint as Chief Scientific Officer and Senior Vice President of the March of Dimes she left to pursue her new position at BMGF.
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Given the prestige of the endowed lecture as well as our guest, please plan to be in person for attendance. There will be a zoom link for hybrid participation for extenuating circumstances and to allow the largest diversity of participation from our campus guests.

Register via Zoom for those not able to attend in person.


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Mar
27
Wed
2024
“Advances Toward the Next Generation Tools For Precision Medicine” – Navonil De Sarkar, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Mar 27 @ 12:10 pm – 1:10 pm

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Presented by

Navonil De Sarkar, PhD
Assistant Professor – Department of Pathology at the Medical College of Wisconsin

About

Navonil De Sarkar is an Assistant Professor at the Medical College of Wisconsin Cancer Center with a dual background in computational and experimental genomics; he brings a multidisciplinary approach to studying human cancers. His research focuses on understanding the natural history of the disease, devising noninvasive approaches to track adaptive and molecular evolutionary changes in cancer accurately, and ultimately developing practical strategies for precision medicine in advanced cancer patients (Augmented precision medicine).

Navonil received his Ph.D. from the Indian Statistical Institute and joined Peter Nelson’s lab at the University of Washington & Fred Hutchinson Cancer Research Center, Seattle, for postdoctoral training. Through adopting integrative genomics approaches, Navonil developed extensive experience analyzing tumor genomes to study functionally relevant mutations and structural aberrations using tumor tissue and circulating tumor DNA (ctDNA). Navonil participated in several large-scale consortium data analyses, including Stat-up-to-cancer germline and prostate tumor analysis efforts. Navonil led the bioinformatics analysis of the large-scale germline sequence work that highlighted the importance of inherited DNA repair genes in shaping the fate of advanced prostate cancer. He is one of the early discoverers of CDK12 loss-associated tandem duplicator signature. Subsequently, De Sarkar developed a machine learning-based classifier that accurately predicts functional homologous recombination deficiency. Recently, he co-led a study interrogating whole genomes of advanced prostate cancers using cell-free DNA sequencing and discovered imprints of cancer epigenomes in native cell-free DNA sequence data.

Navonil is a recipient of several trainee awards. To mention in 2019 Navonil received the very competitive Prostate Cancer Foundation Young Investigator Award. Then onwards, Navonil is co-leading Prostate Cancer Foundation DNA repair-focused working group activities. He is the editorial board member for Translational Oncology and an associate editor for the Genitourinary Oncology edition of Frontiers journals.

Navonil re-joined MCW in March 2023 and committed to establishing a multidisciplinary research group to develop cutting-edge but practical precision medicine tools for prostate and other cancers. Building on strong biological fundamentals and detailed understandings of the disease, De Sarkar Lab (DeTAnomics Lab) is developing novel therapeutic strategies and working to co-develop new genomic assays and computational genomics tools to help us tackle the most lethal types of prostate and other cancers. DeTAnomics Lab adopts long-read genomic sequencing techniques to better understand cancer genome, transcriptome, and epigenome. In the lab, DeTAnomics lab explores the complex interplay between the genome and epigenome to uncover new insights that can lead to the development of more effective therapeutics and biomarkers. Currently, DeSarkar and his team are working on developing a practical strategy to degrade BRCA2 in tumor cells so as to confer DNA-damaging mediated therapy benefits to a wider pool of patients.

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Apr
10
Wed
2024
2024 E. James Aiman Lecture: Sloane L. York, MD, MPH @ Medical College of Wisconsin - Bolger (previously HRC) Auditorium, Medical Education Building
Apr 10 @ 9:00 am – 10:00 am
2024 E. James Aiman Lecture: Sloane L. York, MD, MPH @ Medical College of Wisconsin - Bolger (previously HRC) Auditorium, Medical Education Building

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Featured Speaker: Sloane L. York, MD, MPH – “Reconsidering Abortion Training Post-Dobbs: Why is this integral to OBGYN education?”

About Dr. Chan

Sloane L. York, MD MPH, (she/her), is currently an Associate Professor of Obstetrics and Gynecology division of Complex Family Planning at Rush University Medical Center in Chicago, IL. She completed her residency in OBGYN in 2011 and Family Planning Fellowship in 2013 at Northwestern University, where she also received a Masters in Public Health. Dr. York joined the faculty at Rush in 2013 where she established family planning services and helped develop the Division of Family Planning. Since 2018, she has been the OBGYN Residency Program Director at Rush. Dr. York is also the Associate Program Director for the Complex Family Planning Fellowship at Rush which began in 2022. Additionally, she works as an OB Hospitalist at Rush and is a mom to two very active children.

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