Calendar of Events

Aug
7
Fri
2020
Student-Centered Pipeline to Advance Research in Cancer Careers (SPARCC) Cancer Research Summit and Graduation @ Virtual Event
Aug 7 @ 10:30 am – 12:00 pm

Please join the Department of Obstetrics and Gynecology for the Student-Centered Pipeline to Advance Research in Cancer Careers (SPARCC) Cancer Research Summit and graduation on August 7, 2020, from 10:30 a.m.-12 p.m. This will be a virtual event, where the scholars will have the opportunity to share their research and open it up for questions and brief discussions for each presentation. We will conclude the event by “presenting” graduation certificates and acknowledging each scholar’s participation this summer.

Program:

10:30-11:30 a.m.: Research Presentations – Topics are centered on “wicked problems” found in cancer-specific research.

11:30 a.m.-12 p.m.: Graduation Ceremony – SPARCC Co-Directors Janet Rader, MD, and Kristina Kaljo, PhD, will present each of the scholars with a certificate of completion.

If you would like to attend, please email us at sparcc@mcw.edu.

SPARCC is an intensive 8-week summer program that immerses undergraduate students from backgrounds underrepresented in biomedical research in the complexities of clinical cancer research. To learn more, please visit obgyn.mcw.edu/sparcc.

Nov
9
Mon
2020
Family History in Cancer Screening and Treatment – Elizabeth Hopp, MD @ Virtual
Nov 9 @ 5:45 pm – 7:00 pm


Please join us virtually. This talk will detail what constitutes a significant family history along with discussion of genetic testing. The talk will also touch on management of hereditary cancer syndromes, such as Lynch syndrome and BRCA.

Presentation by: Elizabeth Hopp, MD, Gynecologic Oncologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Nov
10
Tue
2020
Anxiety in Women: Healthy Ways to Respond with Abbey Kruper, PsyD @ Virtual
Nov 10 @ 5:45 pm – 7:00 pm

Please join us virtually to learn basic information about how anxiety can present in women and develop strategies to manage distress in order to have a fuller life.

Presentation by: Abbey Kruper, PsyD, psychologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Nov
18
Wed
2020
Infertility: Fact or Fiction with Bo Rydze, MD @ Virtual
Nov 18 @ 5:45 pm – 7:00 pm


Please join us virtually! This talk is geared towards giving both individuals and couples the knowledge to make informed decisions about how to best go about building their families or preserving their fertility. During this time we will dispel common myths surrounding fertility and answer any questions you may have. We will also cover red flags that could mean a potential risk for infertility down the road.

Presentation by: Bo Rydze, MD, Reproductive Endocrinologist

Register Online

Register online through the link to Froedtert’s classes and events below.

Dec
9
Wed
2020
How Does Preeclampsia Impact Your Pregnancy and Your Future Health with Jennifer Jury McIntosh, DO @ Virtual
Dec 9 @ 5:45 pm – 7:00 pm


Please join us virtually! We will discuss what preeclampsia is and the signs and symptoms to watch for in pregnancy, as well as how it’s managed.

We will also explain the impact of preeclampsia on a woman’s future heart health.

Presentation by: Jennifer Jury McIntosh, DO, Perinatologist

Register Online

Register online through the link to Froedtert’s classes and events below.

May
13
Thu
2021
Autoimmune Disorders and Fertility with Jayme Bosler, MD @ Virtual Event (register below)
May 13 @ 6:00 pm – 7:00 pm

Please join us virtually! Women with existing autoimmune diseases may be at higher risk of infertility and some autoimmune conditions can increase a woman’s risk of miscarriage.

Together we will discuss these conditions and what to do to increase your chances of a successful pregnancy.

We will also explain the impact of preeclampsia on a woman’s future heart health.

Presentation by: Jayme Bosler, MD, Reproductive Endocrinology and Infertility physician

Register Online

Register online through the link to Froedtert’s classes and events below.

May
19
Wed
2021
Patient Education Webinar: Urinary Incontinence with Dr. Emily Davidson @ Virtual Event (register below)
May 19 @ 12:00 pm – 1:00 pm

Urinary issues including urgency and leakage are not something you should have to live with or schedule your life around. Learn about types of leakage and the options that exist for treatment.

Presentation by: Emily Davidson, MD, Urogynecologist

Sep
11
Sat
2021
Black Birth: A Maternal Health Conversation and Resource Fair @ Wisconsin Black Historical Society
Sep 11 @ 11:00 am – 1:00 pm


The Milwaukee Film Festival and Froedtert & the Medical College of Wisconsin present Black Birth: A Maternal Health Conversation and Resource Fair.

The short film Black Birth serves as the backdrop to a community dialogue about the joys, fears, complexities, and disparities of Black motherhood in America and locally in Milwaukee. Following the film screening will be a panel discussion including an OB-GYN physician and resident, community doula, African American breastfeeding expert, and other maternal-fetal care specialists, as well as a resource fair featuring leading health and wellness community partners.


This in-person event is FREE and open to the public. Space is limited to the first 150 people. Masks are REQUIRED and will be provided if needed. There is no virtual option. No Tickets required.

TimeTopic
11:00 AMWelcome and Introduction
11:15 AMShort Film
11:45 AM Discussion
12:15 - 1:00 PMPanel Questions and Discussion

Panelists

  • Moderator: Amy Domeyer-Klenske, MD – Obstetrician and Gynecologist
  • OBGYN Providers: Seema Menon, MD – Obstetrician and Gynecologist and Ciera Oshodi, MD – OBGYN Resident
  • Breastfeeding Expert: Dalvery Blackwell, BA, IBCLC with the African American Breastfeeding Network I
  • Doula
  • Patient
Sep
25
Sat
2021
Ray of Hope 5K Run/ 2K Walk for Ovarian Cancer Research (in person race with virtual option) @ Hoyt Park 1800 N Swan Blvd Wauwatosa, WI US 53226
Sep 25 @ 9:00 am – 12:00 pm
Ray of Hope 5K Run/ 2K Walk for Ovarian Cancer Research (in person race with virtual option) @ Hoyt Park 1800 N Swan Blvd Wauwatosa, WI US 53226

Join us September 25th for the Ray of Hope’s 3rd Annual Race! Help us run or walk to raise funds for ovarian cancer. All proceeds go directly to our researchers working hard to identify novel targets and treatment strategies to cure ovarian cancer.

Ray of Hope is a non-profit organization established in 2018 in the Greater Milwaukee Area in response to the need for more advocacy for ovarian cancer awareness and research. Ray of hope provides philanthropic support to ovarian cancer researchers like us to generate preliminary data to apply for high-risk and high-reward federal grants. Ray of hope believes in the bravery of all women who have fought or are fighting against ovarian cancer. Ray of hope is working for women around the globe to be brave and resilient in the fight against ovarian cancer – – and their bravery should not go unnoticed.

Sunila Pradeep, PhD’s laboratory is partnering in the mission of Ray of Hope by identifying novel targets and treatment strategies to cure ovarian cancer.

Oct
21
Thu
2021
Professionalism Week 2021: Navigating Pandexit – Rebounding from Individual and Collective Challenges @ Virtual Event (register below)
Oct 21 @ 9:00 am – 10:00 am
Professionalism Week 2021: Navigating Pandexit - Rebounding from Individual and Collective Challenges @ Virtual Event (register below)

Please join us as we discuss how groups can successfully navigate collective trauma with the COVID-19 pandemic as a model. It is how we cultivate resilience as a group, foster communication and individually and collectively recover and grow that determines whether an initial trauma will cause additional fall out. We propose to review some best practices for how to collectively navigate “pandexit” or recovery from any traumatic or stressful situation that affects a large group of people. In this session, we will discuss individual and group tools for resilience, go over acute and chronic reactions to trauma and discuss how leadership can steer groups of people into recovery.

Speakers:

      Kate Dielentheis, MD, assistant professor of obstetrics and gynecology
      Kristy Graettinger, MD, associate professor of obstetrics and gynecology
      Abbey Kruper, PsyD, associate professor of obstetrics and gynecology, psychiatry and behavioral medicine

Jan
19
Wed
2022
Professional Development Series – “Psychological Safety – An Essential Ingredient for Teamwork” – Martin Muntz, MD, FACP, January 19th @ Virtual Invite via Outlook
Jan 19 @ 9:00 am – 10:00 am

The Department of Obstetrics & Gynecology invites you to our 2021-2022 Professional Development Series

Guest Speaker:

Martin Muntz, MD, FACP
Professor of Medicine, Curriculum Pillar Director – Robert D. and Patricia E. Kern Institute for the Transformation of Medical Education, Vice-Chair for Faculty Development – Department of Medicine, Division of General Internal Medicine

Dr. Muntz oversees several avenues of Kern Institute work relating to “what and how” students learn in medical school, including topics like interprofessional education, communication skills, clinical reasoning, and leadership skills, as well as tools such as learning communities, reflection, and narrative writing. He also is dedicated to increasing transparency and facilitating culture change in the clinical learning environment, as well as exploring innovative curricular models and schedules.

Jan
26
Wed
2022
Babbette LaMarca, PhD, University of Mississippi Medical Center- to present “The Importance of T and B Lymphocytes in Causing Pathophysiology of Preeclampsia” Jan 26th @ Virtual
Jan 26 @ 12:00 pm – 1:00 pm
Babbette LaMarca, PhD, University of Mississippi Medical Center- to present "The Importance of T and B Lymphocytes in Causing Pathophysiology of Preeclampsia” Jan 26th @ Virtual

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column width=”2/3″][vc_column_text]Please join us for a presentation by Babbette LaMarca, PhD, University of Mississippi Medical Center – “The Importance of T and B Lymphocytes in Causing Pathophysiology of Preeclampsia”

Dr. LaMarca is currently an Associate Professor at the University of Mississippi Medical Center in the Department of Obstetrics and Gynecology and Pharmacology / Toxicology.

Babbette’s laboratory is interested in identifying immune mechanisms that cause hypertension during pregnancy.[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”34047″ style=”vc_box_border_circle_2″ qode_css_animation=””][vc_column_text]

Babbette LaMarca, PhD

[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]Specifically, her research focuses on the interactions between lymphocytes and autoantibodies in the pathophysiology of hypertension in response to placental ischemia. Over the years, they have developed models designed to identify how immune cells or their products cause changes in blood pressure during pregnancy. Moreover, they have developed an autoantibody specific clinically relevant inhibitory peptide to block hypertension and endothelial dysfunction which could have potential clinical use in the future.

They have a strong translational research component with their tight collaborations with the Maternal-Fetal Medicine (MFM) Division in the Obstetrics and Gynecology Department. Dr. LaMarca has served as MFM Thesis Director since 2006. Through this collaboration, they obtain human tissues to study alterations in genes and/or proteins in response to low oxygen environment or placental ischemia. Furthermore, they examine how novel therapeutics may provide an avenue for treatment in preeclamptic women by modulating specific immunopharmacological pathways that play a role in causing hypertension during pregnancy.[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][/vc_column][/vc_row]

Mar
3
Thu
2022
MCW Common Read Spring Book Discussion: “Know My Name” by Chanel Miller – March 3rd @ Virtual via Zoom
Mar 3 @ 12:00 pm – 1:00 pm

[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]Please join us Thursday, March 3rd from 12-1pm to discuss this year’s MCW Common Read Book – “Know My Name” by Chanel Miller. This book gives a first person account of sexual assault survival. Dr. Domeyer-Klenske from the department of OBGYN and Dr. Ho Fung, a licensed psychologist who specializes in PTSD and trauma, will lead the discussion.

Copies of the book are available at the MCW library, and purchasing information can be found at the MCW Common Read webpage.

 

Panelists

  • OBGYN Provider: Amy Domeyer-Klenske, MD – Obstetrician and Gynecologist
  • Licensed Psychologist who specializes in PTSD and Trauma: Rae Anne Ho Fung, PhD, LP
Mar
26
Sat
2022
Black Birth: A Symposium on Black Maternal Health @ Saint Kate Arts Hotel - 139 E KILBOURN AVE, MILWAUKEE, WI 53202
Mar 26 @ 8:00 am – 4:30 pm
Black Birth: A Symposium on Black Maternal Health @ Saint Kate Arts Hotel - 139 E KILBOURN AVE, MILWAUKEE, WI 53202

Please join us for this in-person full day event – “Black Maternal Health Symposium”! It’s Saturday, March 26th from 8am – 4:30pm.

Featuring local healthcare advocates including our own:
– Amy Domeyer-Klenske, MD as a panelist for “Laying the Groundwork: Care Provider Panel Discussion #1” from 10am-11am
– Lisa Lockett-Neumuth, WHNP-BC, CNM talking about “Birth Planning as a Trust Model” from 11:15am-12:15pm

Orienting critical attention to the health disparities and staggering rates of Black maternal mortality, this Milwaukee Film’s 2022 Black Maternal Health Symposium brings together local healthcare advocates for a one-of-a-kind learning experience. What makes this event unique is the use of film to spark dialog between community members and service providers around a wide range of maternal health issues. Harnessing the affective power of cinema to provide insight, confront stigmas and remove barriers to understanding, the Black Maternal Health Symposium offers a variety of participant-driven discussions that humanize complex topics in an approachable manner.

Feb
22
Wed
2023
Precision Pathology and PDX Models for Breast Cancer Drug Response Prediction – Hallgeir Rui, MD, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Feb 22 @ 12:00 pm – 1:00 pm

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Presented by

Hallgeir Rui, MD, PhD
WBCS Endowed Professor of Breast Cancer Research
Vice Chair of Research, Department of Pathology
Director of MCW Tissue Bank
Associate Director of Shared Resources, MCW Cancer Center
Medical College of Wisconsin

About

Hallgeir Rui, MD, PhD is internationally recognized for his research on hormone signaling in breast cancer, and has a strong track record of leadership, mentoring and collaboration. He is the WBCS Endowed Professor of Breast Cancer Research at the Medical College of Wisconsin (MCW), with his primary appointment in the Department of Pathology, and a secondary appointment to the Department of Pharmacology & Toxicology. In addition, Dr. Rui serves as the Associate Director of Basic Science and Shared Resources at the MCW Cancer Center. With his past experience as a Program Leader and Shared Resource Director at the NCI-designated Sidney Kimmel Cancer Center at Thomas Jefferson University, Dr. Rui brings valuable experience to the MCW Cancer Center efforts toward NCI-designation. Dr. Rui serves on the Breast Cancer Translational Research Committee of NRG Oncology.

A central focus of hisresearch is on molecular profiling of solid tumors, with published track record in malignancies of the breast, pancreas, prostate, colon, head and neck and melanomas. Key areas of interest are therapy-relevant protein expression, including pathway-activation status and tumor immunology-related markers, with development of better predictive markers and improved personalized cancer care as the overarching goal. Efforts are dedicated to improving methods and applications for quantitative, multiplex immunohistochemistry (IHC) for single-cell protein marker analyses – histocytometry – in solid tumors.

His laboratory invented novel ultrahigh density tissue arraying technology termed cutting-edge matrix assembly (CEMA) that overcomes limitations of core-based tissue arrays (US patent 8,349,584). Our laboratory, in collaboration with Dr. Kay-Uwe Wagner, developed novel prolactin-humanized NSG-Pro mouse strain for more accurate modeling and drug response testing of human breast cancer and other prolactin receptor-positive cancers, and my team has established a panel of new patient-derived breast cancer xenograft models in NSG-Pro mice.

Dr. Rui has extensive experience in facilitating multidisciplinary and collaborative program projects, including a concluded $6.7 million Promise Project Award funded by Susan G. Komen Foundation. Attesting to the productive use of immunofluorescence-based quantitative histocytometry and tissue arraying technologies for high-throughput application of innovative and nonstandard technologies for immunoprofiling of solid tumors, I led a multidisciplinary team that quantified levels of more than 100 therapy-relevant protein markers in nearly 3,000 breast cancer specimens, using tissue arrays and accompanying clinical data assembled and procured by a consortium of five institutions. As the leader of this consortium, I coordinated extensive efforts to combine tissue resources, data, equipment resources and broad areas of expertise.

Learn more about the WHRP Seminars[/vc_column_text][/vc_column][/vc_row]

Mar
11
Sat
2023
Below the Belt: an Endometriosis Movie Screening and Panelist Discussion Event @ Oriental Theatre
Mar 11 @ 3:00 pm – 5:00 pm

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Below the Belt is a movie that shows personal & inspiring stories of four patients urgently searching for answers to mysterious symptoms. It exposes widespread problems in our healthcare systems that disproportionately affect women, and especially women of color who are less likely to be believed, diagnosed & effectively treated for menstrual health issues.

Through the lens of endometriosis, a disease that affects 1 in 9 women/people, the film shows how women are often dismissed, discounted & disbelieved. From societal taboos and gender bias to misinformed doctors and profit-driven healthcare, the film reveals how millions are effectively silenced and how, by fighting back, they can improve healthcare for everyone.[/vc_column_text][vc_separator type=”normal” thickness=”3″][vc_empty_space height=”12px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column width=”2/3″][vc_column_text]Please join us for this free and personal viewing with a discussion and Q&A session with some of our experts. Please keep in mind this viewing is for ages 14+.[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”34965″ img_size=”full” style=”vc_box_border” onclick=”link_image” qode_css_animation=””][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column][vc_separator type=”normal” thickness=”3″][vc_column_text]

Our expert panelists:

[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column width=”1/4″][vc_single_image image=”31056″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Ben Beran, MD
Assistant Professor; Co-Director, Fibroid Clinic: Alternative to Hysterectomies[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”31064″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Camila Bomtempo, MD
Assistant Professor – Obstetrics & Gynecology[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35009″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Carrie Peterson, MD
Associate Professor – Colorectal Surgery[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35013″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Morgan Briggs, MD
Assistant Professor – Obstetrics & Gynecology[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” z_index=””][vc_column width=”1/4″][vc_single_image image=”35010″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Emorie Harty
Patient to share story[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35011″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Emily Vanderhoef
Patient to share story[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”35034″ style=”vc_box_border_circle” qode_css_animation=””][vc_column_text]Brendalyn Ghazaly
Patient to share story[/vc_column_text][/vc_column][vc_column width=”1/4″][vc_single_image image=”31064″ style=”vc_box_border_circle” qode_css_animation=”” el_class=”hide”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_separator type=”normal” thickness=”3″][vc_column_text]

Agenda:

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  • 3:00pm – Welcome and Introductions
  • 3:10pm – Movie Viewing
  • 4:05pm – Panelist Discussion and Q&As
  • 5:00pm – Conclusion

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Giving:

[/vc_column_text][vc_column_text]You can make a difference by supporting cutting-edge endometriosis research and widespread disease recognition and awareness:

· Call Meg Bilicki at (414) 955-4711 or[/vc_column_text][vc_column_text]

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Our expert panelists include:

Ben Beran, MD (obstetrician, gynecologist and co-director of our Fibroid Clinic), Camila Bomtempo, MD (obstetrician & gynecologist), Carrie Peterson, MD (a colorectal surgeon at MCW), and 2 patients willing to share their story – Emorie Harty and Emily Vanderhoef![/vc_column_text][/vc_column][/vc_row]

Apr
26
Wed
2023
“Epigenetic Regulated Heterogeneity in Endocrine Resistant Breast Cancer” – Victor Jin, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Apr 26 @ 12:00 pm – 1:00 pm

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Presented by

Victor Jin, PhD
Linda T. and John A. Mellowes Endowed Chair of Bioinformatics and Data Analytics
Director, Bioinformatics Shared Resources
Professor, Institute for Health and Equity/Biostatistics
Medical College of Wisconsin

About

Dr. Jin has extensive experience in developing computational and genomics approaches for analyzing various omics-seq data, and runs a systems biology lab with a balanced dry and wet components.

Research Interests:

1) Developing genomics and computational approaches for the identification of three-dimensional (3D) chromatin interactions from the various omics-seq data.
2) Functionally and mechanistically characterizing the roles of epigenetic marks in cancer development and progression using novel techniques such as 3C/ChIP/RT-qPCR, 3D-FISH and CRISPR/Cas9.
3) Adapting/applying genome-wide omics-seq techniques in patient tissues to identify epigenetic-driven therapeutic targets and biomarkers.

Learn more about the WHRP Seminars[/vc_column_text][/vc_column][/vc_row]

Jul
26
Wed
2023
Protein Arginine Methylation: Mechanisms and Therapeutic Vulnerabilities – Wei Xu, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Jul 26 @ 12:00 pm – 1:00 pm

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Presented by

Wei Xu, PhD
Professor of Oncology, Marian A. Messerschmidt
Associate Director,, McArdle Laboratory for Cancer Research
Director of MCW Tissue Bank
Co-Director, Genetic and Epigenetic Mechanism Program, Carbone Cancer Center

About

Dr. Xu’s laboratory explores the protective roles of environmental and nutritional estrogenic compounds in mammals for breast cancer prevention and treatment. Estrogen receptors (ERs) exist in two forms, ERa and ERb, which have opposing roles in cell proliferation. Estrogenic compounds can control balance between mammary cell proliferation and differentiation via stimulating the formation of different forms of ER dimers. Xu lab has developed the Bioluminescent Resonance Energy Transfer (BRET) assays for detecting in vivo homodimerization and heterodimerization of ERa and ERb induced by estrogenic compounds. Biological functions of these estrogenic compounds are currently being investigated in cell-based and breast cancer mouse models. Dr. Xu’s laboratory has also employed biochemical and functional genomic approaches, as well as mouse genetics to decipher the contribution of histone arginine methylation to the epigenetic control of cancer cells. The major focus of Xu lab is on a protein arginine (R) methyltransferase CARM1/PRMT4, a nuclear hormone receptor co-activator. Dr. Xu has identified a number of non-histone substrates for CARM1 and is in the progress of elucidating the functions of protein arginine methylation in breast cancer initiation and progression.

Learn more about the WHRP Seminars[/vc_column_text][/vc_column][/vc_row]

Sep
27
Wed
2023
Application of Human Amniotic Membrane in Tissue Engineering – Bo Wang, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Sep 27 @ 12:00 pm – 1:00 pm

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Presented by

Bo Wang, PhD
Director – Tissue Regenerative Engineering Laboratory (TRE Lab)
Assistant Professor – Department of Biomedical Engineering, The Marquette University and Medical College of Wisconsin

About

Dr. Bo Wang, Director and Principal Investigator of the TRE Lab, received her PhD in Biomedical Engineering from Mississippi State University in 2012 and completed her Postdoctoral Fellowship at Northwestern University’s Feinberg School of Medicine, Department of Surgery, in 2016. She joined the Marquette-MCW Joint Department of Biomedical Engineering in January of 2019 with research interests that include stem cell engineering, hard-tissue engineering and 3D bioprinting, as well as vascular tissue engineering, imaging, modeling and simulation.

The Tissue Regenerative Engineering Laboratory is developing bio-functional engineered tissues that provide advanced therapeutic options for such conditions as birth defects, bone disorders, and liver and vascular diseases. To do this, the TRE Lab will first develop a greater understanding of the biological and molecular processes involved in regenerative regression.

Learn more about the WHRP Seminars[/vc_column_text][/vc_column][/vc_row]

Mar
27
Wed
2024
“Advances Toward the Next Generation Tools For Precision Medicine” – Navonil De Sarkar, PhD @ Ob-Gyn Conference Room #252 (2nd floor Wisconsin Diagnostic Lab Building)
Mar 27 @ 12:10 pm – 1:10 pm

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Presented by

Navonil De Sarkar, PhD
Assistant Professor – Department of Pathology at the Medical College of Wisconsin

About

Navonil De Sarkar is an Assistant Professor at the Medical College of Wisconsin Cancer Center with a dual background in computational and experimental genomics; he brings a multidisciplinary approach to studying human cancers. His research focuses on understanding the natural history of the disease, devising noninvasive approaches to track adaptive and molecular evolutionary changes in cancer accurately, and ultimately developing practical strategies for precision medicine in advanced cancer patients (Augmented precision medicine).

Navonil received his Ph.D. from the Indian Statistical Institute and joined Peter Nelson’s lab at the University of Washington & Fred Hutchinson Cancer Research Center, Seattle, for postdoctoral training. Through adopting integrative genomics approaches, Navonil developed extensive experience analyzing tumor genomes to study functionally relevant mutations and structural aberrations using tumor tissue and circulating tumor DNA (ctDNA). Navonil participated in several large-scale consortium data analyses, including Stat-up-to-cancer germline and prostate tumor analysis efforts. Navonil led the bioinformatics analysis of the large-scale germline sequence work that highlighted the importance of inherited DNA repair genes in shaping the fate of advanced prostate cancer. He is one of the early discoverers of CDK12 loss-associated tandem duplicator signature. Subsequently, De Sarkar developed a machine learning-based classifier that accurately predicts functional homologous recombination deficiency. Recently, he co-led a study interrogating whole genomes of advanced prostate cancers using cell-free DNA sequencing and discovered imprints of cancer epigenomes in native cell-free DNA sequence data.

Navonil is a recipient of several trainee awards. To mention in 2019 Navonil received the very competitive Prostate Cancer Foundation Young Investigator Award. Then onwards, Navonil is co-leading Prostate Cancer Foundation DNA repair-focused working group activities. He is the editorial board member for Translational Oncology and an associate editor for the Genitourinary Oncology edition of Frontiers journals.

Navonil re-joined MCW in March 2023 and committed to establishing a multidisciplinary research group to develop cutting-edge but practical precision medicine tools for prostate and other cancers. Building on strong biological fundamentals and detailed understandings of the disease, De Sarkar Lab (DeTAnomics Lab) is developing novel therapeutic strategies and working to co-develop new genomic assays and computational genomics tools to help us tackle the most lethal types of prostate and other cancers. DeTAnomics Lab adopts long-read genomic sequencing techniques to better understand cancer genome, transcriptome, and epigenome. In the lab, DeTAnomics lab explores the complex interplay between the genome and epigenome to uncover new insights that can lead to the development of more effective therapeutics and biomarkers. Currently, DeSarkar and his team are working on developing a practical strategy to degrade BRCA2 in tumor cells so as to confer DNA-damaging mediated therapy benefits to a wider pool of patients.

Learn more about the WHRP Seminars[/vc_column_text][/vc_column][/vc_row]